Diabetes PCR Array 糖尿病基因表达PCR芯片

类糖尿病基因表达PCR芯片可用于研究与糖尿病的发生、发展、和进展有关的84个基因的表达。此芯片可用于研究肥胖和糖尿病模型,治疗和靶基因预测,并检查在不同的组织或细胞系中各种病症和环境因素对基因表达的影响。利用该芯片研究者即能够利用该芯片简单可靠地同时检测与糖尿病相关的基因表达。
Receptors, Transporters and Channels: ABCC8, ADRB3, AQP2, CCR2, CD28, CEACAM1, CTLA4, GCGR, GLP1R, ICAM1, IL4R, INSR, NSF, RAB4A, SELL (LECAM-1), SLC2A4 (GLUT4), SNAP23, SNAP25, STX4, STXBP1, STXBP2, TNFRSF1A, VAMP3, VAPA.
Nuclear Receptors: PPARA, PPARG. Metabolic Enzymes: ACE, ACLY, ENPP1, FBP1, G6PC, G6PD, GCK, GPD1, GSK3B, HMOX1, IDE, ME1, NOS3, PARP1 (ADPRT1), PRKAA1, PRKAG2, PRKCB, PYGL.
Secreted Factors: AGT, CCL5 (Rantes), GCG, IFNG, IL6, IL10, IL12B, INS, RETN, TGFB1, TNF, VEGFA.
Signal Transduction: AKT2, DUSP4, IGFBP5, IKBKB (IKKbeta), INPPL1 (SHIP2), IRS1, IRS2, MAPK8 (JNK1), MAPK14 (p38 MAPK), PIK3C2B, PIK3CD, PIK3R1, PTPN1 (PTP-1B), TRIB3 (SKIP3).
Transcription Factors: CEBPA, FOXC2, FOXG1, FOXP3, HNF4A, PDX1 (IPF1), NEUROD1, NFKB1, NRF1, PPARGC1A, PPARGC1B, SREBF1, HNF1B, NKX2-1.