Cytoskeleton & Regulators PCR Array 细胞骨架调控因子基因表达PCR芯片

细胞骨架调控因子基因表达PCR芯片可用于研究控制细胞内脚手架的生物合成、组织、聚合、解聚作用的84个基因的表达。芯片上的细胞骨架调节性基因包含钙调蛋白和钙调磷酸酶,激酶和磷酸酶和相关ARF和 RHO蛋白家族成员以及他们的关键调控因子。利用该芯片研究者即能够利用该芯片简单可靠地同时检测调控细胞骨架动态的基因表达。
Actin Filaments: Interacting Proteins: ACTR2, ACTR3, ARPC1B, ARPC2, ARPC3, ARPC4, ARPC5, CALD1, CDC42EP3, CFL1, CYFIP1, CYFIP2, DIAPH1, DSTN, EZR, FSCN2, GSN, IQGAP2, MACF1, PFN2, RDX, SSH1, SSH2, VASP, WASF1, WASL.
Organization & Biogenesis: ARFIP2, ARHGDIB, ARHGEF11, ARPC4, CASK, CDC42, CDC42BPA, ARAP1, CFL1, CRK, DIAPH1, DSTN, EZR, FSCN2, GSN, IQGAP1, LIMK1, LIMK2, NCK1, PFN2, RDX, RHOA, ROCK1, SSH1, SSH2.
Polymerization / Depolymerization: ACTR3, ARHGAP6, ARPC1B, ARPC2, ARPC3, ARPC4, ARPC5, CDC42EP2, DSTN, FNBP1L, GSN, NCK1, NCK2, PFN2, PIKFYVE, RAC1, WAS, WASF1, WASL.
Cortical Cytoskeleton: ARFIP2, CLASP1, CTTN, DSTN, EZR, LLGL1, MAPRE1.
Microtubules: Interacting Proteins: CLASP1, CLASP2, CLIP1, CLIP2, MACF1, MAP4, MAPRE1, MAPRE2, MAPT, MID1, RACGAP1, STMN1.
Organization & Biogenesis: CLASP1, MAPT, MID1, PHLDB2, STMN1.
Polymerization / Depolymerization: CLASP1, CLASP2, MAP4, MAPRE1, MAPRE2, MAPT, STMN1.
Spindle Organization & Biogenesis: AURKA, AURKB, CLASP1, CLASP2, CLIP1, MAPRE1, RACGAP1.
Cell Projections: Axons & Dendrites: BAIAP2, CDK5, CDK5R1, CYFIP1, CYFIP2, MAPT.
Filopodia: BAIAP2, CDC42, CDK5, ARAP1, EZR, MSN, RDX.
Growth Cones: CDK5, CDK5R1, MAPT.
Lamellipodia: ACTR3, ARFIP2, ARPC5, CDK5, CTTN, CYFIP1, CYFIP2, NCK1, PPP1R12A, PPP1R12B, RAC1, RDX, WASL.
Microvilli: EZR, MSN, RDX.
Pseudopodia: CDC42, CDC42EP2.
Ruffles: ARFIP2, CTTN, CYFIP1, CYFIP2, EZR, RAC1, RDX.
Cell Shape, Size, Polarity, Morphogenesis: ARHGEF11, CDC42, CDC42EP2, CDC42EP3, ARAP1, CLASP1, CLASP2, CYFIP1, CYFIP2, EZR, LLGL1, MARK2, MYLK2, SSH1.
Cell Motility / Migion: ACTR2, ACTR3, ARFIP2, ARHGDIB, ARHGEF11, ARPC1B, ARPC2, ARPC3, ARPC5, CALD1, CDK5, CDK5R1, ARAP1, DSTN, MSN, NCK1, PAK4, RAC1, ROCK1, WASF1, WASL.
Cell Cycle & Cell Division: Mitosis: AURKA, AURKB, CCNA1, CCNB2, CIT, CLASP1, CLASP2, CLIP1, MAPRE1, MAPRE2.
Cytokinesis: ARHGEF11, AURKB, AURKC, DSTN,
RACGAP1, ROCK1. Cytoskeleton Adaptor Activity: BAIAP2, MSN, NCK1, NCK2, PAK1.
Calmodulin / Calcineurin: CALD1, CALM1, CASK, IQGAP1, IQGAP2, MYLK, MYLK2, PPP3CA, PPP3CB.
G-Protein Signaling: ARFIP2, ARHGAP6, ARHGDIB, ARHGEF11, CDC42, CDC42EP2, ARAP1, CFL1, CIT, CYFIP1, CYFIP2, DIAPH1, IQGAP1, IQGAP2, LIMK1, LIMK2, MAPK13, RAC1, RACGAP1, RHOA, ROCK1, TIAM1, WAS, WASL.
Kinases & Phosphatases: AURKA, AURKB, AURKC, CASK, CDC42BPA, CDK5, CDK5R1, CIT, LIMK1, LIMK2, MAP3K11, MAPK13, MARK2, MYLK, MYLK2, PAK1, PAK4, PPP1R12A, PPP1R12B, PPP3CA, PPP3CB, ROCK1, SSH1, SSH2.