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保存条件 :4°C
保质期 :详见说明
英文名 :Anethole trithione
库存 :充足
供应商 :medchemexpress(MCE)
CAS号 : 532-11-6
规格 :100mg
Anethole trithione (Synonyms: 茴三硫)
Anethole trithione,一种硫杂环胆碱,是一种胆汁分泌刺激剂。Anethole trithione 可增强唾液分泌并增加 mAChR 受体,可用于口干症的研究。美国medchemexpress(MCE)浙江省一级代理:杭州昊鑫生物科技股份有限公司
MCE中国是全球领先的科研化学品和生物活性化合物供应商,总部位于美国新泽西。我们的产品范围覆盖各种抑制剂、激动剂、API和化合物库。专业、高效的企业灵魂铸造了在行业的卓越地位。热情和充满活力的研发团队拥有着大量的化学和生物科学家。专注于生物活性化合物,拥有着多年的发展历程和丰富的行业经验。从产品的HNMR数据解析到生物活性数据,从客户的询价到产品的售后服务,我们拥有着完善的管理体系,从而保证我们的服务更加高效、准确。努力为中国的医药行业发展注入新的活力,我们将成为您研发工作值得信赖的伙伴。
生物活性 | Anethole trithione, a sulfur heterocyclic choleretic, is a bile secretion-stimulating agent. Anethole trithione enhances salivary secretion and increases mAChRs, and can be used for dry mouth research[1][2]. |
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体外研究 (In Vitro) |
Anethole trithione, a slow-releasing H2S donor, is a bile secretion-stimulating drug or cholagogue that protects the liver via an increase in glutathione levels and phase II detoxifying enzymes. Anethole trithione is a potentially efficacious chemoprevention agent for lung cancer and exerts chemopreventive effects in several target organs, such as the liver and colon, by increasing the detoxification rate of carcinogens in these target organs. Anethole trithione protects blood-brain barrier integrity following cerebral ischemia[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Chronic treatment with Anethole trithione increases the salivary secretion from the rat submaxillary gland induced by electrical stimulation of the parasympathetic nerve and by injection of pilocarpine. In parallel with the enhancement of the salivary secretion, the number of the muscarinic acetylcholine receptors is significantly increased[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 | 240.36 |
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Formula | C10H8OS3 |
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CAS 号 | |||||||||||||||||
中文名称 | 茴三硫;胆维他;茴香脑三硫酮 |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 | In Vitro: DMSO : 12.5 mg/mL (52.01 mM; Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 MCE 网站选购。 |
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参考文献 |
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