AML1/ETO Translocation, Dual Fusion Probe

英文名 ：AML1/ETO Translocation, Dual Fusion Probe

供应商 ：Creative Bioarray

规格 ：5 Tests, 10 Tests

The AML/ETO t(8;21)(q21;q22) specific DNA Probe is optimized to detect the reciprocal translocation t(8;21) in a Dual-Color, Dual-Fusion.AML1 is fused with ETO in the t(8;21)(q21;q22) translocation. The rearrangement is observed in 40% of AML M2 patients and less frequently in subgroups M1 and M4. Overall, 7% of AML cases demonstrate the abnormality. Three-way variants of this rearrangement and the t(3;21) (AML1/EVI1) show that juxtaposition of AML1 to the derivative chromosome is consistent and therefore the critical rearrangement. Know more at: http://www.creative-bioarray.com/AML1-ETO-Translocation,-Dual-Fusion-Probe-FHPC-006-item-4647.htm