ANTI-ADAMTS2 Antibody价格_品牌:BOSTER-丁香通官网

免疫原：A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS2(1189-1204aa KTRNQRIQELIDEMRK), different from the related rat and mouse sequences by three amino acids.

亚型：Rabbit IgG

形态：Lyophilized

保存条件：12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.

克隆性：单克隆

适应物种：Human,Rat,Mouse

抗原来源：Rabbit

库存：现货

供应商：博士德生物

应用范围：WB,IHC-P,IHC-F

浓度：500ug/ml

规格：50ul/100ul/150ul

产品概况

货号	BA2621
产品名称	ANTI-ADAMTS2 Antibody
基因名	ADAMTS2
抗体来源	Rabbit
克隆	Polyclonal
抗体亚型	Rabbit IgG
免疫原	A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS2(1189-1204aa KTRNQRIQELIDEMRK), different from the related rat and mouse sequences by three amino acids.
内容	500ug/ml antibody with PBS ，0.02% NaN3 , 1mg BSA
纯化方式	Immunogen affinity purified.
浓度	500ug/ml
产品形态	Lyophilized
保存条件	12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料	ADAMTS2, A disintegrin and metalloproteinase with thrombospondin motifs 2, also known as procollagen I N-proteinase(PC I-NP), is an enzyme that in humans is encoded by the ADAMTS2 gene. The ADAMTS2 gene contains 22 exons. The human ADAMTS2 gene is mapped to chromosome 5q23-q24 by analysis of somatic cell hybrids. ADAMTS2 is responsible for processing several types of procollagen proteins. Procollagens are the precursors of collagens, the proteins that add strength and support to many body tissues. Specifically, this enzyme clips a short chain of amino acids off one end of the procollagen. This clipping step is necessary for collagen molecules to function normally and assemble into fibrils outside cells.
研究类别	1. Colige, A., Nuytinck, L., Hausser, I., van Essen, A. J., Thiry, M., Herens, C., Ades, L. C., Malfait, F., De Paepe, A., Franck, P., Wolff, G., Oosterwijk, J. C., Smitt, J. H. S., Lapiere, C. M., Nusgens, B. V.Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (type VIIC) and common polymorphisms in the ADAMTS2 gene.J. Invest. Derm. 123: 656-663, 2004.2. Hurskainen, T. L., Hirohata, S., Seldin, M. F., Apte, S. S.ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases: general features and genomic distribution of the ADAM-TS family.J. Biol. Chem. 274: 25555-25563, 1999.
Uniprot ID	ADAMTS2: O95450
推荐配套的二抗和检测试剂	Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。

产品应用细节

为了提供最优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。

应用	稀释度*
Western blot:	1:500-2000
Immunohistochemistry(Paraffin-embedded Section):	1:50-400
Immunohistochemistry(Frozen Section):	1:50-400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

*最优稀释度需要用户自己调试，此处数据仅供参考。

**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。

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[list_product_images]Lane 1: Rat Brain Tissue LysateLane 2: Rat Heart Tissue Lysate|IHC(P): Rat Cardiac Muscle Tissue|IHC(F): Rat Cardiac Muscle Tissue|IHC(F): Rat Trachea Tissue[/list_product_images]