产品详情
文献和实验
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免疫原 :0
亚型 :0
形态 :0
保存条件 :0
克隆性 :单克隆
适应物种 :human
抗原来源 :0
库存 :5-7天
供应商 :博士德生物
应用范围 :WB,FC,ELISA
浓度 :0
规格 :200ul
产品概况
产品名称 | NQO1 Antibody |
---|---|
产品描述 | Anti-NQO1 Antibody validated for WB, FC, ELISA in Human. |
文献引用格式 | NQO1 Antibody (Boster Biological Technology, Wuhan, China. Catalog #BM1933) |
应用范围 | WB, FC, ELISA |
抗体来源 | Mouse |
抗体亚型 | IgG1 |
免疫原 | Purified recombinant fragment of human NQO1 expressed in E. Coli. |
抗体规格 | 200ul/1180元 |
产品详情
克隆 | Monoclonal |
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克隆号 | 单克隆抗体:IgG1;克隆号:1A11 |
产品形态 | Liquid |
内容 | Ascitic fluid containing 0.03% sodium azide. |
储存条件 | 连续使用时4℃存储,保质期六个月;长期存储时建议分装为10ul以上小包装-20℃存储,并避免反复冻融,保质期一年。 |
指标相关信息 (来源: Uniprot.org)
小贴士:你可以利用tissue specificity信息来帮助设计阳性和阴性对照。对此有疑问请联系我们技术服务部门。
基因名 | NQO1 |
---|---|
基因全名 | NAD(P)H dehydrogenase [quinone] 1 |
Tissue Specificity | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. |
Sequence Similarities | NAD(P)H dehydrogenase [quinone] 1;1.6.5.2;Azoreductase;DT-diaphorase;DTD;Menadione reductase;NAD(P)H:quinone oxidoreductase 1;Phylloquinone reductase;Quinone reductase 1;QR1;NQO1;DIA4, NMOR1; |
Uniprot ID | NQO1: P15559 |
指标背景简介
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
产品应用细节
为了提供最优质的抗体,博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
应用 | 稀释度* |
---|---|
Western blotting | 1:100-400 |
Immunohistochemistry in paraffin section | 1:50-200 |
Immunocytochemistry in fixed cells | 1:50-200 |
Flow Cytometry | 1:40-80 |
enzyme-linked immuno sorbent assay | 1:2000 |
*最优稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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入驻年限:17年