Anti-GATA3 Antibody

价格： ￥1180

品牌：BOSTER 品牌认证

货号：BM0886

产品详情

产品概况

产品名称	GATA3 Antibody
产品描述	Anti-GATA3 Antibody validated for IHC, ELISA in Human.
文献引用格式	GATA3 Antibody (Boster Biological Technology, Wuhan, China. Catalog #BM0886)
应用范围	IHC, ELISA
抗体来源	Mouse
抗体亚型	IgG1
免疫原	Purified recombinant fragment of human GATA3 expressed in E. Coli.
抗体规格	200ul/1180元

产品详情

克隆	Monoclonal
克隆号	单克隆抗体；IgG1；克隆号：7B5
产品形态	Liquid
内容	Ascitic fluid containing 0.03% sodium azide.
储存条件	连续使用时4℃存储，保质期六个月；长期存储时建议分装为10ul以上小包装-20℃存储，并避免反复冻融，保质期一年。

指标相关信息 (来源: Uniprot.org)

小贴士：你可以利用tissue specificity信息来帮助设计阳性和阴性对照。对此有疑问请联系我们技术服务部门。

基因名	GATA3
基因全名	Trans-acting T-cell-specific transcription factor GATA-3
蛋白功能	T-cells and endothelial cells.
Tissue Specificity	Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. .
Sequence Similarities	Trans-acting T-cell-specific transcription factor GATA-3;GATA-binding factor 3;GATA3;
Uniprot ID	GATA3: P23771

指标背景简介

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.

产品应用细节

为了提供最优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。

应用	稀释度*
Western blotting	1:100-400
Immunohistochemistry in paraffin section	1:50-200
Immunocytochemistry in fixed cells	1:50-200
Flow Cytometry	1:40-80
enzyme-linked immuno sorbent assay	1:2000

*最优稀释度需要用户自己调试，此处数据仅供参考。

**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。

产品图片

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[list_product_images]Immunohistochemical analysis of paraffin-embedded human Small Intestine, muscularis propria tissues using anti-GATA3 mouse mAb[/list_product_images]