PeproTech重组小鼠R-Spondin-1 250ug

价格：询价

品牌：PeproTech 品牌认证

货号：315-32

产品详情

Recombinant Murine R-Spondin-1

Catalog Number:

315-32

Synonyms:

Roof plate-specific Spondin-1, RSPO1

Description:

R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the family consists of four structurally related secreted ligands (Rspo 1-4), all containing the furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in the adrenal glands, ovary, testis, thyroid, and trachea. Rspo can interact with the Frizzled/LRP6 receptor complex in a manner that stimulates the Wnt/beta-catenin signaling pathway. Recombinant Murine R-Spondin-1 is a 27.1 kDa protein consisting of 245 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions.

AA Sequence:

SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCQEGLYL HKGRCYPACP EGSTAANSTM

Source:

CHO cells

Purity:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells.

Research Interests: