肝癌甲基化PCR芯片Liver Cancer EpiTect Methyl qPCR Array

服务名称 ： 肝癌甲基化PCR芯片

提供商 ：SAbiosciences

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Liver Cancer EpiTect Methyl qPCR Array

肝癌甲基化PCR芯片

Product	Species	Technology	Cat. No.
Liver Cancer EpiTect Methyl qPCR Array	Human	DNA Methylation	EAHS-031Z
Liver Cancer EpiTect Methyl qPCR Array	Mouse	DNA Methylation	EAMM-031Z
Liver Cancer EpiTect Methyl qPCR Array	Rat	DNA Methylation	EARN-031Z

The Human Liver Cancer EpiTect Methyl II Signature PCR Array profiles the methylation status of 22 tumor suppressor gene promoters whose hypermethylation has been reported in the literature to occur frequently in a variety of liver tumors. Profiling tumor samples with these arrays may help correlate CpG island methylation status with biological phenotypes. The results may also provide insights into the molecular mechanisms and biological pathways behind liver cancer development and progression, as well as its pathology. With a simple restriction enzyme digestion and real-time PCR, research studies can analyze the methylation status of 22 different liver cancer genes with this DNA methylation PCR array.
Both 96-well and 384-well ( 4 X 96 ) formats are available.
The EpiTect Methyl II PCR Arrays use the MethylScreen™ Technology provided under license from Orion Genomics, LLC.
肝癌甲基化PCR芯片用于研究文献报道中在各种各样的肝脏肿瘤经常发生甲基化的22个肿瘤抑制基因的启动子甲基化状态。利用该芯片分析肿瘤样本有助于关联CpG岛甲基化状态与生物表型。结果还可进一步洞察肝癌发育和进程，及其病理背后的分子机制和生物学通路。利用这个芯片，通过简单的限制性内切酶消化和实时定量PCR，就可以研究分析22个不同肝癌基因的启动子甲基化状态。

包括96-孔板和384-孔板( 4 X 96 )。
EpiTect甲基二世PCR数组使用MethylScreen™技术提供了在猎户座基因组学的许可下,有限责任公司。
Angiogenesis: EP300.
Apoptosis & Anti-Apoptosis: CDKN1B, CDKN2A, FHIT, PYCARD (TMS1/ASC), TNFRSF10D.
Cell Adhesion & Migration: CDH1, DLC1, OPCML (aOBCAM), RELN.
Cell Cycle, Growth, Differentiation & Development: CCND2 (Cyclin D2), CDKN1A, CDKN1B (p27KIP1), CDKN2A, DLC1, EP300, FHIT, RASSF1, WT1.
Cytokine Receptor: TNFRSF10D.
Cytokine Signaling Inhibitor: SOCS1.
DNA Damage Repair: CDKN1A, MSH2, MSH3, RASSF1.
Drug Metabolism: GSTP1.
Extracellular Matrix Remodeling: RELN.
Histidine Triad Gene Family: FHIT.
Inflammation: PYCARD (TMS1/ASC).
Oncogene: E2F1.
Transcription Factors: E2F1, EP300, RUNX3, WT1, EP300.
Tumor Suppressor Gene Candidates: DLEC1, CDKN1A, CDKN2A, E2F1, MSH2, MSH3, RASSF1, RUNX3.
WNT Signaling Pathway: SFRP2.