重组大鼠 ALK-1 / ACVRL1 蛋白 (His & Fc标签)

保存条件 ：-20℃ to -80℃

保质期 ：12个月

英文名 ：Rat ALK-1 / ACVRL1 Protein (His & Fc Tag)

库存 ：99

供应商 ：北京义翘神州科技股份有限公司

CAS号 ：无

规格 ：200 µg

重组大鼠 ALK-1 / ACVRL1 蛋白 (His & Fc标签)（产品说明）
蛋白名称：Rat ALK-1 / ACVRL1 Protein (His & Fc Tag)
蛋白构建：A synthetic DNA sequence encoding the rat ACVRL1 (NP_071886.1) extracellular domain (Met 1-Ala 118) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953.The ED50 for this effect is typically 40-200 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Asp 17
蛋白分子量：The secreted recombinant rat ACVRL1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer comprises 343 amino acids with a predicted molecular mass of 38.7 kDa. As a result of glycosylation, it migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号：NP_071886.1
蛋白氨基酸序列：Met1-Ala118
蛋白标签：C-human IgG1-Fc & His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.