HIV-1 gp41 Antibody

免疫原 ：KLH-conjugated synthetic peptide encompassing a sequence within the C-term of HIV-1 gp41.

亚型 ：Rabbit Ig

形态 ：Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

保存条件 ：Store at -20°C.

克隆性 ：多克隆抗体

标记物 ：见下方详细说明

适应物种 ：Vs

宿主 ：Rabbit

应用范围 ：E, WB, IHC

浓度 ：见详细说明信息

靶点 ：HIV-1 gp41

抗体英文名 ：HIV-1 gp41 Antibody

抗体名 ：HIV-1 gp41 Antibody

规格 ：0.1 mg

HIV-1 gp41 Antibody产品详细介绍：

产品名称：	HIV-1 gp41 Antibody
说明书：	http://www.abbiotec.com/antibodies/hiv-1-gp41-antibody【参考图片】
货号：	250695
规格：	0.1 mg
产品描述：	The transmembrane protein gp41 (TM) acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane. The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm. The gp120-gp41 heterodimer seems to contribute to T-cell depletion during HIV-1 infection.
克隆类型：	Rabbit Polyclonal Antibody
亚型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within the C-term of HIV-1 gp41.
适用物种：	Vs
应用范围：	E, WB, IHC
应用说明：	E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
别名：	Envelope glycoprotein gp160; Env polyprotein; Transmembrane protein; TM; Glycoprotein 41; gp41; Human immunodeficiency virus type 1; HIV-1
形态：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
保存条件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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