p62/SQSTM1 Antibody (CY5546)

免疫原 ：Q13501

形态 ：62kDa

保存条件 ：-20度

适应物种 ：Human Mouse Rat

应用范围 ：WB ICC/IF FC

抗体英文名 ：p62/SQSTM1 Antibody

规格 ：50ul/100ul

Product Datasheet		www.abways.com
p62/SQSTM1 Antibody Catalog No: CY5546 Reactivity: Human Mouse Rat Isotype: Rabbit IgG Applications: WB ICC/IF FC
UniProt ID: Q13501 All Names: OSIL; Oxidative stress induced like; p60; p62; p62B; Paget disease of bone 3;PDB 3; PDB3;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 62 kDa
WB: 1:5000~1:10000 ICC/IF: 1:50~1:200 FC: 1:50
Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels.
Western blot analysis of p62/SQSTM1 expression in SKBR-3 cell lysate.
http://www.abways.cn/showproduct.asp?cid=CY5546
For Research Use Only. Not For Use In Diagnostic Procedures. www.abways.com