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SU6656

CAS No. : 330161-87-0

MCE 国际站：SU6656

产品活性：SU6656 是 Src 家族激酶抑制剂，抑制 Src，Yes，Lyn，Fyn 的 IC₅₀分别为 280，20，130，170 nM。SU6656 可抑制 FAK Y576/577、 Y925、Y861 位点的磷酸化。SU6656 还能抑制p-AKT。

研究领域：Protein Tyrosine Kinase/RTK  |  PI3K/Akt/mTOR

作用靶点：Src  |  FAK  |  Akt

In Vitro: SU6656 decreases phosphorylation of Src family kinases (SFKs) in HNSCC cells.

In Vivo: SU6656 (2-4 mg/kg; i.p.; once) significantly decreases ischemic postconditioning (IPoCo) mediated increase in fall down time.

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