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英文名 :Murine BD-2
库存 :大量
供应商 :PeproTech(派普泰克)
CAS号 :无
Recombinant Murine BD-2
Catalog Number:
250-40
Synonyms:
Beta-Defensin 2, DEFB2, DEFB4A, Skin-Antimicrobial Peptide 1, SAP1
Description:
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-2 is a 5.5 kDa protein containing 51 amino acid residues.
AA Sequence:
AVGSLKSIGY EAELDHCHTN GGYCVRAICP PSARRPGSCF PEKNPCCKYM K
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Not available.
Research Interests:
Country of Origin:
USA
派普泰克生物科技(苏州)有限公司(PeproTech中国)
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入驻年限:15年