Anti-Mouse CD226 (DNAM-1) Functional Grade Purified 功能抗体 Clone: 10E5

抗体名 ：Mouse CD226 抗体

抗体英文名 ：CD226 DNAM1, PTA1, Tlisa

靶点 ：Clone: 10E5

浓度 ：1 mg/mL

应用范围 ：Flow Cytometric Analysis, Functional Assays

宿主 ：Rat

适应物种 ：Mouse

标记物 ：Functional Grade Purified (low endo, azide-free)

克隆性 ：多克隆

保存条件 ：Store at 2-8°C.

亚型 ：IgG2b

规格 ：50 ug

Description: This 10E5 monoclonal antibody reacts with mouse CD226, which is also known as DNAX accessory molecule-1 (DNAM-1). CD226 is an adhesion molecule expressed primarily on T cells, including thymocytes. The highest levels of CD226 are found on naïve CD8 T cells. Moreover, expression of CD226 is regulated differentially in CD4 T cells. Under certain culture conditions, CD226 can be upregulated in Th1 and downregulated in Th2 and Th0 cells. This cell surface receptor can also be detected on natural killer cells, some B cell subsets, monocytes, and platelets. Interaction with its ligands, the poliovirus receptor (CD155) and CD112, results in adhesion and cell signaling events that promote innate and adaptive immunity, including differentiation, survival, and cytotoxicity.

The 10E5 monoclonal antibody has been reported to inhibit antigen-specific T cell proliferation and IFN-gamma production in vivo.
Product Information

Contents: Anti-Mouse CD226 (DNAM-1) Functional Grade
Purified
Catalog Number: 16-2261
Clone: 10E5
Concentration: 1 mg/mL
Host/Isotype: Rat IgG2b
Handling Conditions: Use in sterile environment.

Endotoxin Level: Less than 0.001 ng/ug antibody, as
determined by the LAL assay.

Formulation: aqueous buffer, no sodium azide
Temperature Limitation: Store at 2-8°C.
Batch Code: Refer to Vial
Use By: Refer to Vial