文献支持肝S9库/Liver S9 Pooled

价格： ￥225

品牌：CHI Scientific 品牌认证

货号：6-1200-A

产品详情

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保存条件：-80℃

保质期：2年

英文名：Liver Pooled S9

库存：大量

供应商：齐氏生物

CAS号：N/A

规格：0.5ml、20mg/ml

肝细胞S9是肝实质细胞匀浆液的去线粒体上清液，包含了大量的CYPs等药物代谢酶，对于研究化合物的药物代谢和考察潜在的药物药物相互作用是非常有用的研究工具，同时也是食品、化妆品、化学品等致突变试验（Ames)重要试剂。

规格型号

产品优势

1. 技术优势：申报2项国家发明

2. 质量优势：批量制备、严格质检，符合工业客户试验需求

3. 客户优势：合作国内多家GLP安评机构、省级疾控、省级药检、药物CRO公司

4. 行业优势：入选丁香通2020“研选”推荐试剂

公司拥有冷冻保存的肝细胞和肝亚细胞组分的完整产品线，可用于ADME研究、诱导、抑制、体内清除率和代谢等研究。我们提供的肝亚细胞组分（包括肝微粒体、CYP450酶类、肝S9等），同时根据客户需要我们提供特定种属的定制化服务。

论文引用

1）Int. J. Environ. Res. Public Health 2021, 18(15), 8095; https://doi.org/10.3390/ijerph18158095
Mutagenicity Assessment to Pesticide Adjuvants of Tolluene, Chloroform, and Trichloroethylene by Ames Test

2）Int J Environ Res Public Health. 2020 Feb 6;17(3). pii: E1025. doi: 10.3390/ijerph17031025.
Assessment of Biological Toxicity and Ecological Safety for Urban Black-Odor River Remediation.
Xu RR^1,2, Pei ZT^1,2, Wang WQ^1,2, Zhang M^1,2, Zhang LL^1,2, Zhang J^1,2, Wang WQ^1,2, Sun LW^1,2, Zhang YM³.

3) Mutat Res Genet Toxicol Environ Mutagen. 2019 Feb;838:22-27.doi:10.1016/j.mrgentox.2018.11.015. Epub 2018 Dec 1.
Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.
Du X¹, Gao S², Hong L¹, Zheng X³, Zhou Q⁴, Wu J⁵.

4） Int J Environ Res Public Health. 2018 Sep 2;15(9). pii: E1907. doi: 10.3390/ijerph15091907.
Evaluation by the Ames Assay of the Mutagenicity of UV Filters Using Benzophenone and Benzophenone-1.
Wang WQ^1,2, Duan HX³, Pei ZT^4,5, Xu RR^6,7, Qin ZT⁸, Zhu GC^9,10, Sun LW^11,12.

5) J Control Release. 2018 Jun 10;279:220-233. doi: 10.1016/j.jconrel.2018.04.034. Epub 2018 Apr 19.
Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease.
Wang P¹, Zheng X¹, Guo Q¹, Yang P¹, Pang X¹, Qian K¹, Lu W², Zhang Q³, Jiang X¹.

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该产品被引用文献

S9系列产品论文引用（部分）

1) Int J Environ Res Public Health. 2018 Sep 2;15(9). pii: E1907. doi: 10.3390/ijerph15091907.
Evaluation by the Ames Assay of the Mutagenicity of UV Filters Using Benzophenone and Benzophenone-1.
Wang WQ^1,2, Duan HX³, Pei ZT^4,5, Xu RR^6,7, Qin ZT⁸, Zhu GC^9,10, Sun LW^11,12.

2) Mutat Res Genet Toxicol Environ Mutagen. 2019 Feb;838:22-27. doi: 10.1016/j.mrgentox.2018.11.015. Epub 2018 Dec 1.
Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.
Du X¹, Gao S², Hong L¹, Zheng X³, Zhou Q⁴, Wu J⁵.

3) Mutat Res Genet Toxicol Environ Mutagen. 2019 Feb;838:22-27. doi: 10.1016/j.mrgentox.2018.11.015. Epub 2018 Dec 1.
Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.
Du X¹, Gao S², Hong L¹, Zheng X³, Zhou Q⁴, Wu J⁵.

4) Int J Environ Res Public Health. 2020 Feb 6;17(3). pii: E1025. doi: 10.3390/ijerph17031025.
Assessment of Biological Toxicity and Ecological Safety for Urban Black-Odor River Remediation.
Xu RR^1,2, Pei ZT^1,2, Wang WQ^1,2, Zhang M^1,2, Zhang LL^1,2, Zhang J^1,2, Wang WQ^1,2, Sun LW^1,2, Zhang YM³.

5) Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapy

Article in Journal of Materials Chemistry B 6(40) · September 2018 with 20 Reads

6) J Control Release. 2018 Jun 10;279:220-233. doi: 10.1016/j.jconrel.2018.04.034. Epub 2018 Apr 19.
Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease.
Wang P¹, Zheng X¹, Guo Q¹, Yang P¹, Pang X¹, Qian K¹, Lu W², Zhang Q³, Jiang X¹.

7) EBioMedicine. 2018 Nov;37:246-258. doi: 10.1016/j.ebiom.2018.10.041. Epub 2018 Oct 23.
Salvianolic acid A targeting the transgelin-actin complex to enhance vasoconstriction.
Zhong W¹, Sun B², Gao W³, Qin Y¹, Zhang H¹, Huai L⁴, Tang Y⁴, Liang Y⁴, He L⁴, Zhang X⁴, Tao H⁴, Chen S², Yang W², Yang L², Liu Y², Liu H¹, Zhou H⁵, Sun T⁶, Yang C⁷.