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免疫原 :Peptide derived from human Cdc14A.
亚型 :Rabbit Polyclonal IgG
形态 :液态
保存条件 :保存于-20℃
克隆性 :多克隆
标记物 :无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种 :Hu, Mo, Rat, Dog, Cow, Hor, Sheep
保质期 :按说明书条件可保存1-2年
抗原来源 :见详细说明资料
目录编号 :PL0306685
级别 :超纯
库存 :大量
供应商 :华拓生物
宿主 :Rabbit
应用范围 :WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 ICC: 1:100-500
浓度 :1mg/ml
靶点 :Cdc14A
抗体英文名 :Cdc14A Antibody
抗体名 :细胞周期调控因子14A抗体
规格 :0.1ml
Cdc14A Antibody
Cat#:PL0306685
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human Cdc14A.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
In budding yeast, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis. Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family. It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53. In addition, Cdc14a dephosphorylates hCdh1 and activates APCCdh1. Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, mitosis and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells.
Alternate Names:
CDC 10; Cdc 14; Cdc 14A; Cdc 14A1; Cdc 14A2; CDC10; CDC14 cell division cycle 14 homolog A; CDC14 homolog A; Cdc14A1; Cdc14A2; Cell division cycle 14 homolog A; Dual specificity protein phosphatase Dual specificity protein phosphatase CDC14A; hCDC14; CC14A_HUMAN.
Specificity Reaction:Hu, Mo, Rat, Dog, Cow, Hor, Sheep
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 ICC: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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入驻年限:13年