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免疫原 :Peptide derived from human TNFRSF14.
亚型 :Rabbit Polyclonal IgG
形态 :液态
保存条件 :保存于-20℃
克隆性 :多克隆
标记物 :无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种 :Hu, Dog, Hor
保质期 :按说明书条件可保存1-2年
抗原来源 :见详细说明资料
目录编号 :PL0305486
级别 :超纯
库存 :大量
供应商 :华拓生物
宿主 :Rabbit
应用范围 :WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500 FC: 1:100-500 ICC: 1:100-500
浓度 :1mg/ml
靶点 :TNFRSF14/HVEM
抗体英文名 :TNFRSF14/HVEM Antibody
抗体名 :肿瘤坏死因子受体超家族成员14抗体
规格 :0.1ml
TNFRSF14/HVEM Antibody
Cat#:PL0305486
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human TNFRSF14.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
TNFRSF14 is a type I membrane protein belonging to the TNF receptor superfamily. This receptor mediates herpes virus entry into cells during infection. TNFRSF14 is able to inhibit the proliferation, activation, and cytokine production of T cells. It has an extracellular domain containing several cysteine-rich repeats and a short cytoplasmic region containing a TRAF (TNF receptor-associated factor) interaction domain. The extracellular domain of TNFRSF14 interacts with the herpes simplex virus envelope glycoprotein D. TNFRSF14 binds two cellular ligands: lymphotoxin alpha and LIGHT. LIGHT is a transmembrane protein expressed and shed from the surface of activated T cells, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes. The LIGHT:TNFRSF14 interaction controls immune response functions by cell death induction as well as cell activation.
Alternate Names:
HVEM; Tumor necrosis factor receptor superfamily member 14; HVEML; ATAR; CD258; CD258 antigen; CD40 like protein precursor; Herpesvirus entry mediator A; Herpesvirus entry mediator; Herpesvirus entry mediator ligand; HVEA; HVEM L; HVEML; LIGHT; LIGHTR; TNFSF 14; TR2; Tumor necrosis factor receptor like gene2; TNR14_HUMAN.
Specificity Reaction:Hu, Dog, Hor
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500 FC: 1:100-500 ICC: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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入驻年限:13年