染色体浓缩调控蛋白1抗体

价格： ￥2400

品牌：PL Laboratories

货号：PL0304986

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免疫原：Peptide derived from human RCC1.

亚型：Rabbit Polyclonal IgG

形态：液态

保存条件：保存于-20℃

克隆性：多克隆

标记物：无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）

适应物种：Hu, Mo, Rat, Pig, Cow

保质期：按说明书条件可保存1-2年

抗原来源：见详细说明资料

目录编号：PL0304986

级别：超纯

库存：大量

供应商：华拓生物

宿主：Rabbit

应用范围：WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500

浓度：1mg/ml

靶点：RCC1

抗体英文名：RCC1 Antibody

抗体名：染色体浓缩调控蛋白1抗体

规格：0.1ml

RCC1 Antibody

Cat#：PL0304986

Isotype:Rabbit Polyclonal IgG

Immunogen：Peptide derived from human RCC1.

Purification: Immunogen affinity purified

Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

Background：

Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis. The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin. RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, RCC1, with chromatin , but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, and, where bound, to increase the affinity of chromatin for NE membranes.

Alternate Names：

Cell cycle regulatory protein; CHC 1; CHC1; Chromosome condensation 1; Chromosome condensation protein 1; Guanine nucleotide releasing protein; HERC2; Ran GEF; RanGEF; RCC 1; RCC1 I; Regulator of chromosome condensation 1; Regulator of chromosome condensation; SHEP1; RCC1_HUMAN.

Specificity Reaction：Hu, Mo, Rat, Pig, Cow

Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500

Storage ：

Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

This product for research use only, not for use in humans, therapeutic or diagnostic procedures.

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