泛素蛋白连接酶抗体

价格： ￥2400

品牌：PL Laboratories

货号：PL0303962

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免疫原：Peptide derived from human MAFbx.

亚型：Rabbit Polyclonal IgG

形态：液态

保存条件：保存于-20℃

克隆性：多克隆

标记物：无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）

适应物种：Hu, Mo, Rat, Dog, Pig, Cow, Hor,

保质期：按说明书条件可保存1-2年

抗原来源：见详细说明资料

目录编号：PL0303962

级别：超纯

库存：大量

供应商：华拓生物

宿主：Rabbit

应用范围：WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500

浓度：1mg/ml

靶点：MAFbx/Fbx32

抗体英文名：MAFbx/Fbx32 Antibody

抗体名：泛素蛋白连接酶抗体

规格：0.1ml

MAFbx/Fbx32 Antibody

Cat#：PL0303962

Isotype:Rabbit Polyclonal IgG

Immunogen：Peptide derived from human MAFbx.

Purification: Immunogen affinity purified

Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

Background：

Fbx32 is an E3 ubiquitin ligase that initiates ATP dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. It is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. It is also thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. Fbx32 interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD.

Alternate Names：

Fbx32; 4833442G10Rik; AI430017; Atrogin 1; Atrogin-1; ATROGIN1; Atrophy gene 1; F box only protein 32; F-box only protein 32; F-box protein 32; FBX32_HUMAN; fbxo25; FBXO32; FLJ32424; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F box; Muscle atrophy F box protein; Muscle atrophy F-box protein.

Specificity Reaction：Hu, Mo, Rat, Dog, Pig, Cow, Hor,

Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500

Storage ：

Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

This product for research use only, not for use in humans, therapeutic or diagnostic procedures.

PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。