转录调节因子MAZR抗体价格_品牌:PL Laboratories-丁香通官网

免疫原：Peptide derived from human PATZ1.

亚型：Rabbit Polyclonal IgG

形态：液态

保存条件：保存于-20℃

克隆性：多克隆

标记物：无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）

适应物种：Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, ,

保质期：按说明书条件可保存1-2年

抗原来源：见详细说明资料

目录编号：PL0303058

级别：超纯

库存：大量

供应商：华拓生物

宿主：Rabbit

应用范围：WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500

浓度：1mg/ml

靶点：PATZ1

抗体英文名：PATZ1 Antibody

抗体名：转录调节因子MAZR抗体

规格：0.1ml

PATZ1 Antibody

Cat#：PL0303058

Isotype:Rabbit Polyclonal IgG

Immunogen：Peptide derived from human PATZ1.

Purification: Immunogen affinity purified

Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

Background：

PATZ1 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12).The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein.

Alternate Names：

BTB POZ domain zinc finger transcription factor; Mazr; PATZ; POZ (BTB) and AT hook containing zinc finger 1; POZ , AT hook, and zinc finger containing protein 1; Protein kinase A RI subunit alpha associated protein; RIAZ; Transcription factor MAZR; ZBTB19; Zfp278; Zinc finger and BTB domain containing protein 19; Zinc finger protein 278; Zinc finger protein 278, isoform CRA_d; Zinc finger sarcoma gene protein; ZNF278; ZSG.

Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, ,

Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500

Storage ：

Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

This product for research use only, not for use in humans, therapeutic or diagnostic procedures.

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