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免疫原 :PhosphoPeptide derived from human FAK around the phosphorylation site of Tyr861.
亚型 :Rabbit Polyclonal IgG
形态 :液态
保存条件 :保存于-20℃
克隆性 :多克隆
标记物 :无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种 :Hu, Mo, Rat, Chi, Dog, Cow, Hor
保质期 :按说明书条件可保存1-2年
抗原来源 :见详细说明资料
目录编号 :PL0302850
级别 :超纯
库存 :大量
供应商 :华拓生物
宿主 :Rabbit
应用范围 :WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
浓度 :1mg/ml
靶点 :Phospho-FAK(Tyr861)
抗体英文名 :Phospho-FAK(Tyr861) Antibody
抗体名 :磷酸化粘着斑激酶抗体
规格 :0.1ml
Phospho-FAK(Tyr861) Antibody
Cat#:PL0302850
Isotype:Rabbit Polyclonal IgG
Immunogen:PhosphoPeptide derived from human FAK around the phosphorylation site of Tyr861.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion.
Alternate Names:
FAK (phospho Y861); p-FAK (phospho Y861); FADK 1; FADK; FAK 1; FAK related non kinase polypeptide; FAK1; Focal adhesion kinase 1; FRNK; pp125FAK; Protein tyrosine kinase 2; Protein Tyrosine Kinase Cytoplasmic; PTK 2; FAK1_HUMAN; Focal adhesion kinase-related nonkinase; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK.
Specificity Reaction:Hu, Mo, Rat, Chi, Dog, Cow, Hor
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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入驻年限:13年