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免疫原 :Peptide derived from human CYP2R1 (274-313aa).
亚型 :Rabbit Polyclonal IgG
形态 :液态
保存条件 :保存于-20℃
克隆性 :多克隆
标记物 :无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种 :Hu, Mo, Rat, Dog, Pig, Hor
保质期 :按说明书条件可保存1-2年
抗原来源 :见详细说明资料
目录编号 :PL0302452
级别 :超纯
库存 :大量
供应商 :华拓生物
宿主 :Rabbit
应用范围 :WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
浓度 :1mg/ml
靶点 :CYP2R1
抗体英文名 :CYP2R1 Antibody
抗体名 :细胞色素P450 2R1
规格 :0.1ml
CYP2R1 Antibody
Cat#:PL0302452
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human CYP2R1 (274-313aa).
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake.
Alternate Names:
Cytochrome P450 2R1; Cytochrome P450 family 2 R1; Cytochrome P450 family 2 subfamily R polypeptide 1; EC 1.14.13.15; MGC4663; Vitamin D 25 hydroxylase.
Specificity Reaction:Hu, Mo, Rat, Dog, Pig, Hor
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。
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入驻年限:13年