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免疫原 :E.coli-derived rat IL1 beta recombinant protein.
亚型 :Rabbit Polyclonal IgG
形态 :液态
保存条件 :保存于-20℃
克隆性 :多克隆
标记物 :无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种 :Rat
保质期 :按说明书条件可保存1-2年
抗原来源 :见详细说明资料
目录编号 :PL0403054
级别 :超纯
库存 :大量
供应商 :华拓生物
宿主 :Rabbit
应用范围 :WB: 1:100-500 E: 1:100-500
浓度 :1mg/ml
靶点 :IL1 beta
抗体英文名 :IL1 beta Antibody
抗体名 :IL1 beta抗体
规格 :0.1ml
IL1 beta Antibody
Cat#:PL0403054
Isotype:Rabbit Polyclonal IgG
Immunogen:E.coli-derived rat IL1 beta recombinant protein.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Interleukin-1beta (IL-1beta) is a potent stimulator of bone resorption whose gene is mapped to 2q14, and has been implicated in the pathogenesis of high bone turnover and osteoporosis. IL-1beta, a prominent microglia-derived cytokine, caused oligodendrocyte death in coculture with astrocytes and microglia, but not in pure culture of oligodendrocytes alone. It also can cause nuclear export of a specific NCOR corepressor complex, resulting in derepression of a specific subset of nuclear factor-kappa-B (NFKB)-regulated genes. Furthermore, Microenvironmental IL-1beta and, to a lesser extent, IL-1alpha are required for in vivo angiogenesis and invasiveness of different tumor cells. Additional, the cooperation of IL-1beta and PDGFB induces contractile-to-synthetic phenotype modulation of human aortic smooth muscle cells in culture.
Alternate Names:
Catabolin antibody;H1 antibody;Hematopoietin 1 antibody;IFN beta inducing factor antibody;IL 1 antibody;IL 1 beta antibody;IL 1B antibody.
Specificity Reaction:Rat
Application Notes:WB: 1:100-500 E: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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入驻年限:13年