Cyclin D3 Antibody

免疫原 ：KLH-conjugated synthetic peptide encompassing a sequence within the center region of human cyclin D3.

亚型 ：Rabbit Ig

形态 ：Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and antigen affinity chromatography.

保存条件 ：Store at -20°C.

克隆性 ：多克隆

标记物 ：见下方详细说明

适应物种 ：H, M, R

宿主 ：Rabbit

应用范围 ：E, WB, IHC

浓度 ：见详细说明信息

靶点 ：Cyclin D3

抗体英文名 ：Cyclin D3 Antibody

抗体名 ：Cyclin D3 Antibody

规格 ：0.1 mg

Cyclin D3 Antibody产品详细介绍：

产品名称：	Cyclin D3 Antibody
说明书：	【点击查看详细说明及参考图片】
货号：	254527
规格：	0.1 mg
产品描述：	Cyclin D3 (CCND3) is a regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Cyclin D3 hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenic and antimitogenic signals. Cyclin D3 is also a substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, it is required for nuclear translocation and activity of the cyclin D-CDK4 complex.
克隆类型：	Rabbit Polyclonal Antibody
亚型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human cyclin D3.
适用物种：	H, M, R
应用范围：	E, WB, IHC
应用说明：	E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
别名：	Cyclin D3; G1/S-specific cyclin-D3; CCND3
形态：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and antigen affinity chromatography.
保存条件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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