RNA专用转染试剂-R4000

供应商 ：英格恩

小RNA转染。包括siRNA转染，miRNA，mimic，inhibitor等。长链的和shRNA转染,针对和长链的等RNA转染优化。
可转染动物细胞、昆虫细胞等，也可以转染原代细胞、悬浮细胞和原代细胞等传统难转染细胞。

●最新转染试剂，纳米聚合物，转染效果优于脂质体转染试剂。 ●高效转染，沉默效率高，可以达到90％以上的沉默效率。 ●低细胞毒性，有血清转染，无须反复更换培养基。 ●原代细胞、悬浮细胞和敏感细胞都能转。

应用于本产品的文献

1. Tumour Biol. 2016 Mar. MiR-30a regulates the proliferation, migration, and invasion of human osteosarcoma by targeting Runx2.（MiR-30a通过靶向作用于小家畜相关的转录因子2（Runx2）进而调节人骨肉瘤细胞的增值、迁移及侵袭）

2. PLoS One. 2015 Mar 31. MicroRNA-22 impairs anti-tumor ability of dendritic cells by targeting p38.（MicroRNA-22 通过靶向作用于p38蛋白削弱树突状细胞的抗肿瘤能力）

3.Mol Biosyst. 2015 Nov The involvement of aquaporin 1 in the hepatopulmonary syndrome rat serum-induced migration of pulmonary arterial smooth muscle cells via the p38-MAPK pathway.（肝肺综合征相关的研究）

4. J Immunol. 2015 Aug 1. MicroRNA-9 Regulates the Differentiation and Function of Myeloid-Derived Suppressor Cells via Targeting Runx1（MicroRNA-9 通过靶向作用于Runx1调节髓源性抑制细胞的分化和功能）

5.Immunol Res. 2015 Jun. Decreased expression of microRNA-125a-3p upregulates interleukin-23 receptor in patients with Hashimoto’s thyroiditis.（microRNA-125a-3p的低表达可以上调淋巴瘤性（样）甲状腺肿病人白细胞介素-23受体的水平）.

6.Int J Mol Med. 2015 Dec. miR-21 synergizes with BMP9 in osteogenic differentiation by activating the BMP9/Smad signaling pathway in murine multilineage cells.（miR-21激活小鼠干细胞中BMP9 /Smad信号通路与BMP9 协同作用于成骨细胞分化的研究）

7.J Biol Chem. 2010 Apr 2;285(14):10890-901.Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction.

8.Apoptosis. 2010 Apr;15(4):488-98.A PKC-beta inhibitor protects against cardiac microvascular ischemia reperfusion injury in diabetic rats.

9.Microvasc Res. 2010 Jan 14. A PKC-beta inhibitor treatment reverses cardiac microvascular barrier dysfunction in diabetic rats.

10.J Immunol. 2011 Apr 15;186(8):4716-24.Both miR-17-5p and miR-20a Alleviate Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating STAT3 Expression.

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