Acetyl Lysine antibody

是否单克隆 ：2

抗体英文名 ：Acetyl Lysine antibody

库存 ：大量

应用范围 ：,

适应物种 ：,

宿主 ：rabbit

抗原来源 ：ot

规格 ：100µg

Catalog Number	Pack Size	Price
ICP0380-100	100µg	￥1750.00

Species: Rabbit

Formulation: 250 µg/mL antibody stored in PBS, pH 7, with 50% glycerol

Storage & Stability: Store product at –20⁰C. Three years from date of shipping

Immunogen: Acetylated KLH conjugates

Purification: The antibody was purified on acetyl-lysine agarose

Specificity: The antibody recognizes proteins acetylated on lysine residues. Tested: acetylated histone, acetylated BSA, and acetylated MBP, no reaction to the non-acetylated proteins

Scientific Description: DNA transcription can not take place unless DNA is unwound from the nucleosomes. The cell unwinds the DNA by acetylation of lysine residues within the proteins. It has been suggested that acetylation of non-histones proteins (e.g., transcription factors) and histones may be involved. Acetylation of the proteins may result in signal transduction within the chromatic domains.

References: Zeng, L. et al FEBS Lett. 2002, 513, 124-128 (2002) Kim. S. et al Molecular Cell, Volume 23, Issue 4, Pages 607-618