Human IL-1RL1 / ST2 Protein, Fc Tag

英文名 ：Human IL-1RL1 / ST2 Protein, Fc Tag

库存 ：In Stock

供应商 ：ACROBiosystems

规格 ：1mg

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>90% as determined by SDS-PAGE.

活性:


产品背景:
Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.

产品描述:
Human IL-1RL1, Fc Tag is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 61 kDa. The predicted N-terminus is Lys 19. The reducing (R) protein migrates as 85-100 kDa in SDS-PAGE due to glycosylation.