重组人粒细胞巨噬细胞刺激因子（rHuGM-CSF）

价格：询价

品牌：特宝生物

货号：SJA01

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保质期：36个月

保存条件：-20℃~-70℃

英文名：Recombinant Human GM-CSF

库存：现货

供应商：特宝生物

CAS号：无

规格：10μg、50μg

品名	rHuGM-CSF
规格	10μg、50μg
描述	重组人粒细胞巨噬细胞刺激因子是一个单链的非糖基化多肽链，含128个氨基酸残基，两对二硫键，分子量约为14.6kD，E. coli 表达。
来源	大肠杆菌（E. coli）。
分子量	约为14.6kD。
纯度	≥97%。
内毒素含量	<1EU/µg，鲎试剂法测定。
活性	用细胞增殖的方法进行测定，TF-1细胞依赖株，比活性≥1×10⁷IU/mg。
配方	本品为无菌冻干粉，缓冲体系为10mM磷酸盐缓冲液。
复溶	建议使用0.2ml无菌水复溶。
保存	冻干样品自生产之日起在-20℃到-70℃可以稳定保存36个月。溶解以后，该细胞因子能在2-8℃的无菌条件下保存一个月，或在-20℃到-70℃的人工除霜的冰箱中保存三个月，而无明显活性损失。避免反复冻融。

GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils. GM-CSF has also been reported to have a functional role on non-hematopoietic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. GM-CSF is species specific and human GM-CSF has no biological effects on Mouse cells.
仅供实验室使用。