前列腺素E合成酶抗体

前列腺素E合成酶抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

前列腺素E合成酶抗体产品介绍

PTGES由白介素-1β诱导产生，可能参与P53诱导的凋亡过程。
Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
mol wt:17kDa
Other Aliases:
Prostaglandin E synthase; Glutathione S transferase 1 like 1; MGC10317; MGST IV; MGST1 L1; MGST1 like 1; MGST1L1; MGSTIV; Microsomal glutathione S transferase 1 like 1; p53 induced apoptosis protein 12; p53 induced gene 12; PGES; PIG 12; PIG12; PP 102; PP 1294; PP102; PP1294; PTGES; TP53I12; Tumor protein p53 inducible protein 12
前列腺素E合成酶抗体