Cathepsin-A / CTSA抗体

保存条件 ： 常温，避光

克隆性 ：单克隆

抗体名 ：Cathepsin-A / CTSA抗体

Cathepsin-A / CTSA抗体产品信息

免疫原 :
Recombinant mouse CTSA protein ( Catalog#50348-M08H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant mouse CTSA ( rM CTSA ; Catalog#50348-M08H ; P16675-1 ; Met 1 - Tyr 474 ). CTSA specific IgG was purified by mouse CTSA affinity chromatography
Cathepsin-A / CTSA抗体背景综述
Mouse cathepsin A / lyososomal carboxypeptidase A, is a lysosomal serine protease with structural homology to yeast carboxypeptidase Y. This enzyme is synthesized as a 54kDa precursor/zymogen and is processed into a catalytically active 32 and 20kDa two-chain form. linked by disulfide bonds. In addition to its carboxypeptidase activities at acidic pH, cathepsin A also serves as a multicatalytic enzyme with deamidase and esterase activities at neutral pH. Also identified as a lyososomal protective protein distinct from its catalytic function., cathepsin A associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers, and provides a protective role for stability and activity. Cathepsin A defects are linked to multiple forms of Galactosialidosis with a combined secondary deficiency of beta-galactosidase and neuraminidase. It has been shown that the cathepsin A precursor has the potential to restore both beta-galactosidase and neuraminidase activities in vivo. Additionally, extralysosomal cathepsin A plays a role in regulation of bioactive peptide functions because of its hydrolyzation activity.
Cathepsin-A / CTSA抗体相关产品如下：
hz-11165R Sidekick 2细胞粘附分子伴侣蛋白2抗体
hz-11166R SorLA/LRP9低密度脂蛋白受体相关蛋白9抗体
hz-8530R SDHC琥珀酸细胞色素亚基B560抗体
hz-9846R Streptokinase链激酶抗体
hz-11333R AP180装配衔接蛋白180抗体
hz-11330R SORCS1液泡蛋白分选受体SORCS抗体
hz-11312R SSX2滑膜肉瘤X染色体相关2抗体
hz-11315R MPP3突触相关蛋白102抗体
hz-11316R SAPAP3PSD95结合蛋白3抗体
hz-10067R SP-C肺表面活性蛋白C抗体
hz-12046R 5HT1D Receptor5-羟色胺受体1D抗体
hz-12047R 5HT1E Receptor5-羟色胺受体1E抗体
hz-12048R 5HT1F Receptor5-羟色胺受体1F抗体
hz-12049R 5HT2A Receptor5-羟色胺受体2A抗体
hz-12050R 5HT2B Receptor5-羟色胺受体2B抗体
hz-12051R 5HT3A Receptor5-羟色胺受体3A抗体
hz-12052R 5HT3D + 5HT3E Receptor5-羟色胺受体3D+3E抗体
hz-12053R 5HT3D Receptor5-羟色胺受体3D抗体
hz-12054R 5HT4 Receptor5-羟色胺受体4抗体
hz-12055R 5HT5A receptor5-羟色胺受体5A抗体
hz-12056R 5HT7 Receptor5-羟色胺受体7抗体
hz-7875R SCELSCEL蛋白抗体
hz-7876R SPAG8精子相关抗原8抗体
hz-7874R SART1T淋巴细胞识别的鳞状细胞癌抗原抗体
hz-7873R S100 alpha 2S100A2抗体
hz-7901R SPDYA细胞周期G2/M期快速诱导蛋白SPDYA抗体
hz-12058R 5HT6 Receptor5-羟色胺受体6抗体
hz-6402R SMARCA2ATP依赖解旋酶SMARCA2抗体
hz-8389R SKP1S期激酶相关蛋白1抗体
hz-8390R SHFM3SHFM3蛋白抗体
hz-8329R SRXN1硫氧还蛋白1抗体
hz-7878R STAM信号转导衔接蛋白1抗体
hz-5332R phospho-SLK (Tyr530)磷酸化酪氨酸蛋白激酶Fyn/同步原癌基因抗体
hz-9027R SPTLC2丝氨酸棕榈酰转移酶2抗体
hz-5616R Phospho-Smad3 (Ser425)磷酸化细胞信号转导分子SMAD3抗体
hz-5617R Phospho-Smad3 (Ser208)磷酸化细胞信号转导分子SMAD3抗体
hz-5618R Phospho-Smad2(Thr220)磷酸化细胞信号转导分子SMAD2抗体
hz-5627R phospho-Alpha synuclein (Tyr125)磷酸化核突触蛋白α抗体
hz-5628R phospho-Alpha synuclein(Ser129)磷酸化核突触蛋白α抗体
hz-5630R phospho-SYN1(Ser549)磷酸化神经突触素1抗体
hz-5631R phospho-SYN1(Ser603) 磷酸化神经突触素1抗体
hz-5632R phospho-SYN1(Ser62+Ser67)磷酸化神经突触素1抗体
hz-5639R phospho-STXBP1 (Ser515)磷酸化神经突触前膜胞内蛋白抗体
hz-5974R SMYD3组蛋白甲基转移酶SMYD3抗体
hz-5975R SSX8滑膜肉瘤X断点蛋白8抗体
hz-5622R phospho-STAT6(Thr645)磷酸化信号转导和转录激活因子6抗体
hz-5623R Phospho-Stathmin(Ser25)磷酸化原癌基因蛋白18
hz-6257R STK38丝氨酸/苏氨酸蛋白激酶38抗体
hz-2945R SNX1分选连接蛋白1抗体
hz-6159R STARD8GTP酶激活因子STARD8抗体