CD28抗体

免疫原 ：Human CD28 transfected murine T cell hybridoma.

亚型 ：IgG1

形态 ：液体

保存条件 ：Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.

克隆性 ：单克隆

适应物种 ：Human

宿主 ：兔

应用范围 ：WB, IP, IHC-Fr, Functional Studies, ICC, Flow Cyt

浓度 ：100 µg 浓度为 1 mg/ml

靶点 ：CD28

抗体英文名 ：Anti-CD28 antibody

抗体名 ：CD28抗体

规格 ：100ug

CD28抗体产品信息

免疫原 :
Recombinant Human CD28 protein (Catalog#11524-H08H)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Human CD28 (rh CD28; Catalog#11524-H08H; P10747-1; Met 1-Pro 152). CD28 specific IgG was purified by Human CD28 affinity chromatography.
CD28抗体Background
T-cell-specific surface glycoprotein CD28, also known as TP44 and CD28, is a single-pass type I membrane protein which contains oneIg-like V-type (immunoglobulin-like) domain. CD28 / TP44 is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. CD28 / TP44 is expressed in T-cells and plasma cells, but not in less mature B-cells. CD28 / TP44 is involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. CD28 / TP44 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. CD28 / TP44 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
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