ALPI / IAP抗体

保存条件 ： 常温，避光

克隆性 ：单克隆

抗体名 ：ALPI / IAP抗体

ALPI / IAP抗体产品信息

免疫原 :
Recombinant Human ALPI / IAP protein (Catalog#13225-H08H)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Human ALPI / IAP (rh ALPI / IAP; Catalog#13225-H08H; P09923; Met1-Asp503). ALPI / IAP specific IgG was purified by Human ALPI / IAP affinity chromatography.
ALPI / IAP抗体Background
Alkaline phosphatase, intestinal also known as ALPI is digestive brush-border enzyme which is upregulated during small intestinal epithelial cell differentiation. ALPI is also referred to as IAP and it is released into the lumen after a high-fat diet. ALPI / IAP is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. Lysophosphatidylcholine (LysoPC) releases IAP into the apical medium more than other intestinal brush-border enzymes, sucrose, aminopeptidase N, and lactase, without comparable lactate dehydrogenase release or cell injury. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver / bone / kidney (tissue non-specific). Intestinal ALP shows 86.5% amino acid identity to placental ALP and 56.6% amino acid identity to liver / bone / kidney ALP.
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