BACE抗体(C末端)|BACE Antibody (CT) (BACE (CT). Asp2)

BACE抗体(C末端)|BACE Antibody (CT) (BACE (CT). Asp2)

价格: ¥1

品牌:艾美捷BioVision

货号:5051-100

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克隆性 :多克隆

抗体英文名 :BACE Antibody (CT) (BACE (CT). Asp2)

规格 :100 ug

产品名称:BACE抗体(C末端)|BACE Antibody (CT) (BACE (CT). Asp2)

【产品形式】:艾美捷为您提供的BACE抗体(C末端)产品为无色溶液形式,含有100 ug抗体.该产品浓度为1 mg/ml,溶解于包含有0.02 % NaN3的PBS缓冲液中.请在收到该BACE抗体(C末端)产品后,将其置于-20 °C冷冻保存,建议分装使用以避免反复冻融.

【背景资料】:Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer’s disease. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by two proteases. APP is first cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide, which is deposited in the brains of all suffers of Alzheimer’s disease. The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2). BACE/Asp2 is a novel transmembrane aspartic protease and colocalizes with APP.

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点击:BACE抗体(C末端),查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。

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关键词:BACE,BACE抗体(C末端)

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