基质细胞衍生因子－1抗体

基质细胞衍生因子－1抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

基质细胞衍生因子－1抗体产品介绍

基质细胞衍生因子－1(SDF-1)又称趋化因子CXCL12 是小分子的细胞因子，属于趋化因子蛋白家族。它有两种形式, SDF-1α/CXCL12a和SDF-1β/CXCL12b。趋化因子有四个保守的半胱氨酸残基形成两对双硫键以构成趋化因子的特殊结构。第一第二半胱氨酸残基之间隔着一个介入氨基酸残基。
基质细胞源性生长因子1:趋化因子CXCL12对淋巴细胞有强烈的趋化作用并在发育中起重要作用。在胚胎发育中CXCL12引导造血干细胞从胎儿肝脏到骨髓的迁徙。 CXCL12可以在许多组织(包括脑,胸腺,心,肺,肝,肾,骨髓,脾脏)中表达。
趋化因子CXCL12的受体是CXCR4。但是,最近有人认为CXCL12还可以与CXCR7受体结合。
The cell source growth factor 1: tend to turn the factor CXCL12 to have tend of mightiness to the lymphoid cell to turn the function and rise the important function in the growth.The CXCL12 leading builds the blood stem cell in embryo develop from embryo's liver to the change residence of marrow. CXCL12 can expression in many tissues ( include the brain, thymus gland, heart, lung, liver, kidney, marrow, spleen). Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members contain an RCxC motif which may be a general requirement for binding to CXC chemokine receptors; those with the ELR motif are chemotatic for neutrophils and have been shown to be angiogenic, while those without the motif act on T and B cells, and are typically angiostatic; exist as monomers and dimers, but are believed to be functional as monomers; found only in vertebrates and a few viruses.
mol wt:9.8kDa
Other Aliases:
Sdf1; stromal cell derived factor-1; Chemokine (C X C motif) ligand 12; CXCL12; hIRH; PBSF; Pre B cell growth stimulating factor; SCYB12; SDF 1 alpha; SDF 1; SDF 1 beta; SDF 1b; SDF1; SDF1a; SDF1b; Stromal cell derived factor 1; TLSF a; TLSF b; TLSFa; TLSFb; TPAR1xy-13581R ZBTB5锌指蛋白ZBTB5抗体
xy-13582R ZBTB6锌指蛋白ZBTB6抗体
xy-13583R ZBTB7C锌指蛋白ZBTB7C抗体
xy-13584R ZBTB8A锌指蛋白ZBTB8A抗体
xy-13585R ZBTB8B锌指蛋白916B抗体
xy-13574R ZBTB4锌指蛋白903抗体
xy-13575R ZBTB40锌指蛋白923抗体
xy-6503R ZNF288锌指蛋白288抗体
xy-6119R ZNF185锌指蛋白185抗体
xy-6120R ZNF431锌指蛋白431抗体
xy-6200R ZNF379锌指蛋白379抗体
xy-8463R ZNF804A锌指蛋白804A抗体
xy-5716R ZNF693锌指蛋白693抗体
xy-13570R ZBTB3锌指蛋白ZBTB3抗体
xy-9732R ZWILCH着丝粒ZWILCH蛋白抗体
xy-12252R ZFP57锌指蛋白57抗体
xy-12232R ZNF717锌指蛋白717抗体
xy-12088R ZDHHC7锌指蛋白370抗体
xy-12216R ZNF3锌指蛋白3抗体
xy-12220R ZNF423锌指蛋白423抗体
xy-12218R ZNF239锌指蛋白239抗体
xy-12219R ZNF426锌指蛋白426抗体
xy-12222R phospho-ZNF598(Tyr306)磷酸化锌指蛋白598抗体
xy-11973R ZNF423锌指蛋白423抗体
xy-7782R zinc finger protein 830锌指蛋白830抗体
xy-13550R ZAR1L受精卵抑制蛋白1样蛋白抗体
基质细胞衍生因子－1抗体