产品详情
文献和实验
相关推荐
保存条件 :蓝冰
克隆性 :多克隆
规格 :25 ug
上海科敏生物经销国内外知名品牌试剂抗体,折扣低,货期快,欢迎新老客户咨询订购!Purified anti-human IL-33参数介绍>>>>
Clone | BL35172 |
Isotype | Mouse IgG1, κ |
Reactivity | Human; This antibody does not cross react with mouse IL-33. |
Immunogen | Mature recombinant protein human Interleukin-33 (Ser112-Thr270) |
Formulation | This antibody is provided in phosphate-buffered solution, pH 7.2, 0.09% sodium azide. |
Preparation | The antibody was purified by affinity chromatography. |
Concentration | 0.5mg/ml |
Recommended Usage | Each lot of this antibody is quality control tested by Western blotting. For Western blotting applications, a concentration of 1 µg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application. " |
Applications | WB - Quality tested |
Application Notes | The optimal concentration should be determined by titration for each individual assay of interest. |
Description | IL-33, also known as NFHEV and DVS 27, is a 30 kD proinflammatory protein that belongs to IL-1 superfamily. IL-33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL1α or IL1β stimulation. IL-33 interacts with IL1RL1/ST2 receptor and IL-1 receptor accessory protein (IL1RAP) in order to activate intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. Recombinant IL-33 has been shown to enhance Th2-associated immune responses and potently increase mast cell proliferation and cytokine production. |
Storage | Upon receipt, store undiluted at 4°C. |
品牌介绍:Biolegend公司自2002年成立以来,一直致力于为生物医药研究领域提供一流的,高质量的流式抗体、试剂盒及其它相关产品。公司聚集了一批来自PharMingen的专业杰出人士,建立了一支雄厚技术背景的专业队伍,并通过其自身的先天优势,以及与世界知名实验室和研究所的良好合作关系,以最合理的价格为广大客户提供卓越的免疫学和细胞生物学产品,并不断地开发新产品,以满足飞速发展的生命科学研究的需要。短短几年时间,Biolegend公司得到了飞速发展,已跻身全球最先进的抗体公司行列,并在2009年成为美国哈佛大家的独家抗体供应商!Biolegend公司的试剂主要包括细胞免疫、细胞因子、趋化因子、粘附分子等及与癌症研究、T 调节细胞研究、干细胞研究、先天免疫研究、细胞周期分析、凋亡研究及特定修饰类抗体等领域相关的试剂,用于流式、ELISA、免疫沉淀、WB、免疫荧光、免疫组化、及体内体外功能学试验。其中,Biolegend公司的流式抗体以其具有较宽范围的荧光选择及较高的性价比,为广大科研工作者所接受!同时,公司配备了一支经验丰富的技术服务队伍,为客户提供完美的配色方案及快速的售后处理服务!
上海恪敏生物科技有限公司
实名认证
金牌会员
入驻年限:12年