Purified anti-PI3K p110 δ

保存条件 ：蓝冰

克隆性 ：多克隆

规格 ：200 ul

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Purified anti-PI3K p110 δ参数介绍>>>>

Clone	Poly6049
Isotype	Rabbit Polyclonal
Reactivity	Human
Immunogen	Recombinant (partial) Amino acid residues 450-550
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol.
Preparation	The antibody was purified by antigen-affinity chromatography.
Recommended Usage	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 µl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Applications	WB - Quality tested
Description	PI3K p110 delta (phosphatidylinositol-4,5-biphosphate 3-kinase catalytic subunit delta isoform) is a member of the PI3/PI4 kinase family containing a B-Zip domain. This 110 kD protein autophosphorylates, but does not phosphorylate p85 like PI3K p110 δ. PI3K p110 delta exhibits a broad phosphoinositide lipid substrate specificity and is required for directional movement in neutrophils, and is involved in B and T cell receptor complex signaling. This isoform interacts with SH2/SH3 domain-containing p85 adaptor proteins and GTP-bound Ras and consists of catalytic p110 and regulatory p85 subunits and is activated by IL-3, IL-4 and SCF. PI3K is modified by phosphorylation. The Poly6049 antibody recognizes human PI3K p100 delta and has been shown to be useful for Western blotting.
Storage	Upon receipt, store frozen at -20° C.