Anti-Mouse CD34 FITC

克隆性 ：单克隆

应用范围 ：FC

抗体英文名 ：Anti-Mouse CD34 FITC

抗体名 ：Anti-Mouse CD34 FITC

规格 ：50ug

The RAM34 monoclonal antibody reacts with mouse CD34, also known as mucosialin.
It has been reported that the RAM34 antibody can be used to detect CD34+Sca-1+c-Kit+ cells.
CD34 is a highly glycosylated (approximately 90-120 kDa) member of the sialomucin family and is
expressed by capillary endothelial cells, bone marrow stroma, and a small subpopulation of
mouse bone marrow cells. RAM34 has been used to purify mouse hematopoietic stem cells (HSC)
to near homogeneity. CD34 expressed on endothelial cells is a ligand for CD62L and plays a
role in adhesion. Simultaneous staining of mouse bone marrow cells with a cocktail of antibodies
to lineage markers (CD3, CD11b, Ly6G, TER-119 and CD45R/B220) reveals a subset of cells that
stain with the RAM34 antibody and express undetectable to low levels of the indicated lineage markers.