LAMP2 Antibody

LAMP2 Antibody - Product infoApplication
WB, IFPrimary AccessionP13473Other AccessionNP_054701.1ReactivityMouseIsotypeIgG1,KClone Names157CT16.6.6Calculated MW44961 DaLAMP2 Antibody - Additional infoGene ID3920Other Names
LAMP2; Lysosome-associated membrane glycoprotein 2; CD107 antigen-like family member B; CD_antigen=CD107b; Flags: PrecursorTarget/Specificity
This LAMP2 monoclonal antibody is generated from mouse immunized with LAMP2 recombinant protein.Dilution
WB~~1:100~1000
IF~~1:10~50Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Precautions
LAMP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.LAMP2 Antibody - Protein InformationNameLAMP2Function
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.Cellular Location
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membraneTissue Location
Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver