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Catalog N : 08CON002
ω-Conotoxin MVIIC / Omega conotoxin MVIIC
Blocker of P/Q and N-type Ca2+ channels
ω-conotoxin MVIIC (omega conotoxin MVIIC) has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q and N-type calcium channels. It inhibits presynaptic Ca2+ channels, including the Ca2+ channels responsible for Ca2+ uptake by rat brain synaptosomes, the P-type Ca2+ channels in cerebellar Purkinje cells, and a significant fraction of ω-conotoxin GVIA-resistant currents in hippocampal CA1 neurons. ω-conotoxin MVIIC also presents an inhibition of ω-conotoxin GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats. |
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ω-conotoxin MVIIC technical information
AA sequence: Cys1-Lys-Gly-Lys-Gly-Ala-Pro-Cys8-Arg-Lys-Thr-Met-Tyr-Asp-Cys15-Cys16-Ser-Gly-Ser-Cys20-Gly-Arg-Arg-Gly-Lys-Cys26-NH2
Disulfide bonds: Cys1-Cys16, Cys8-Cys20 and Cys15-Cys26
Length (aa): 26
Formula: C106H178N40O32S7
Molecular Weight: 2750.20 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: [147794-23-8]
Source: Synthetic
Purity rate: > 97 %
08CON002-00100 | ω-conotoxin MVIIC | 0.1mg |
08CON002-00500 | ω-conotoxin MVIIC | 0.5mg |
08CON002-01000 | ω-conotoxin MVIIC | 1mg |
北京群晓科苑生物技术有限公司
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入驻年限:12年