Y型聚乙二醇NHS酯

Y型聚乙二醇NHS酯

价格: 询价

品牌:JenKem

货号: Y-PEG-SCM

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保质期 :1年

英文名 :Y-shape PEG NHS Ester

库存 :大量

供应商 :JenKem

CAS号 :

保存条件 :本品应在惰性气体保护下避光密闭冷冻保存, 零下20度

规格 :1g,5g,10g等

Y型NHS是JenKem的自主研发的Y型结构,具有2个PEG链和一个活性酯基因,可以用来生产蛋白或其他生物分子中的赖氨酸上的氨基进行反应。Y-NHS可以在PH=7-8的缓冲液中在较短的时间内与NH2进行聚乙二醇化。由于Y-NHS具有独特的空间结构使它更具有选择性。

产品代号:Y-PEG-NHS

产品纯度:≥ 95%

包装规格:1g, 10g, 100g等(特殊包装需收取分装费用)

分子量:2000 Da, 5000 Da, 10000 Da等

  




产品文献:
 References:
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  3. Guo, L., et al., Application Instructions for Y-NHS-40K for Amine PEGylation, click link.
  4. Masao, H., et al., Chemically Modified Interleukin-6 Aptamer Inhibits Development of Collagen-Induced Arthritis in Cynomolgus Monkeys, Nucleic Acid Therapeutics, 2015.
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  12. Dai, C.Y., et al., Linkage with cathepsin B-sensitive dipeptide promotes the in vitro and in vivo anticancer activity of PEGylated tumor necrosis factor-alpha (TNF-α) against murine fibrosarcoma, Science China Life Sci, 2011, 54(2): 128–138.
  13. Menkhorst, E., et al., Vaginally Administered PEGylated LIF Antagonist Blocked Embryo Implantation and Eliminated NonTarget Effects on Bone in Mice, PLoS ONE, 2011, 6 (5) e19665.
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