Interferon Regulatory Factor(IRF)

Interferon Regulatory Factor(IRF)

价格: ¥700

品牌:prospec

货号:CYT-292

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保存条件 :冷藏/冷冻

保质期 :-20°C

英文名 :Interferon Regulatory Factor-3 Human Recombinant

库存 :大量

供应商 :上海经科化学科技有限公司

CAS号 :

规格 :5μg/20μg/1mg

重组人干扰素调节因子(IRF)相关产品

Interferon Regulatory Factor-1 Human Recombinant
Interferon Regulatory Factor-2 Human Recombinant
Interferon Regulatory Factor-3 Human Recombinant

Interferon Regulatory Factor-5 Human Recombinant


重组人干扰素调节因子1(IRF 1)
重组人干扰素调节因子2(IRF 2)
重组人干扰素调节因子3(IRF 3)
重组人干扰素调节因子5(IRF 5)

重组人Interferon-Induced Protein With Tetratricopeptide Repeats 3(IFIT3)
重组人干扰素α1(IFN a 1)
重组人干扰素α1a(IFN a 1a)
重组人干扰素α1b(IFN a 1b)
重组人干扰素α2a(IFN a 2a)
重组人干扰素α2a,HEK(IFN a 2a)
重组人干扰素α2a,烟草(IFN a 2a)
重组人干扰素α2b(IFN a 2b)
重组人干扰素α2b 20kd聚乙二醇(IFN a 2b)
重组人干扰素α2b,HEK(IFN a 2b)
重组人干扰素α2b,Yeast(IFN a 2b)
重组人干扰素α14(IFNA14)
重组人干扰素α7(IFNA7)
重组人干扰素β1a(IFN b 1a)
重组人干扰素β1b(IFN b 1b)
重组小鼠干扰素β,His Tag(IFN b)
重组人干扰素γ诱导蛋白30(IFI30)
重组马干扰素γ(IFN g)
重组人干扰素γ(IFN g)
重组人干扰素γ,His Tag(IFN g)
重组小鼠干扰素γ(IFN g)
重组大鼠干扰素γ(IFN g)
重组人干扰素γ139 a.a(IFNG 139 a.a)
重组犬干扰素γ(IFNG)
重组人干扰素γ,HEK(IFNG)

重组羊干扰素(IFN)
重组人干扰素Ω1(IFNW1)


重组人干扰素调节因子(IRF)相关产品说明书

Interferon Regulatory Factor-1 Human Recombinant说明书:
Catalogue Number CYT-449
Synonyms IRF-1, IRF1, MAR.
Introduction IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-A, IFN-B, and IFN-G stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines.
Description Interferon Regulatory Factor-1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 134 amino acids (1-114) with a His Tag of 20 aa, and having a molecular mass of 15 kDa.
The IRF-1 is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered colorless solution.
Formulation 1 mg/ml in 20mM Tris pH-8 and 10% glycerol.
Stability Liquid Interferon although stable at 10°C for 1 week, should be stored below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity Greater than 90.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Amino acid sequence MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKHAAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP.

Interferon Regulatory Factor-2 Human Recombinant说明书:
Catalogue Number CYT-534
Synonyms IRF-2, IRF2, MAR, DKFZp686F0244, Interferon regulatory factor 2.
Introduction Interferon regulatory factor 2 is a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. IRF2 binds to the upstream regulatory region of type-1 IFN and IFN-inducible MHC class-1 genes (the interferon consensus sequence (ics) and represses those genes.
Description Interferon Regulatory Factor-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 133 amino acids (1-113) with a His Tag of 20 aa, and having a molecular mass of 15 kDa.
The IRF2 is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered colorless solution.
Formulation 1 mg/ml in 20mM Tris pH-8, 1mM DTT and 10% Glycerol.
Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMHAARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIKKGNNAFRVYR MLP.

Interferon Regulatory Factor-3 Human Recombinant说明书:
Catalogue Number CYT-292
Synonyms IRF-3, IRF3, Interferon Regulatory Factor 3.
Introduction Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. IRF-3 mediates interferon-stimulated response element (isre) promoter activation. Functions as a molecular switch for antiviral activity. Dsrna generated during the course of an viral infection leads to IRF3 phosphorylation on the c-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with creb binding protein (crebbp) to form dsrna-activated factor 1 (draf1), a complex which activates the transcription of genes under the control of isre. The complex binds to the ie and prdiii regions on the ifn-alpha and ifn-beta promoters respectively. IRF-3 does not have any transcription activation domains.
Description IRF-3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 111 amino acids (1-112) and having a molecular mass of 13 kDa.
The Interferon Regulatory Factor-3 is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered colorless solution.
Formulation 1mg/ml in phosphate-buffered saline (PBS), pH 7.4.
Stability Liquid Interferon although stable at 10°C for 1 week, should be stored below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity Greater than 95.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Amino acid sequence MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALNRKEGL RLAEDRSKDP HDPHKIYEFV NS.

Interferon Regulatory Factor-5 Human Recombinant说明书:
Catalogue Number CYT-816
Synonyms Interferon Regulatory Factor 5, IRF-5, SLEB10, IBD14.
Introduction Interferon Regulatory Factor-5, also known as IRF5 belongs to the interferon regulatory factor (IRF) family, a group of transcription factors with various functions, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, IRF5 is implicated in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. IRF5 is activated by TLR7 or TLR8 signaling.
Description IRF5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (176-240a.a) and having a molecular mass of 10.7kDa.
IRF5 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation IRF5 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Purity Greater than 85% as determined by SDS-PAGE.
Amino Acid Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I

(其他干扰素相关产品说明书请向客服索取)

重组人干扰素调节因子(IRF)相关产品索引
IFIT3 Human
IFN a 1 Human
IFN a 1a Human
IFN a 1b Human
IFN a 2a Human
IFN a 2a Human, HEK
IFN a 2a Human, Plant
IFN a 2b Human
IFN a 2b Human, 20 kd PEG
IFN a 2b Human, HEK
IFN a 2b Human, Yeast
IFN b 1a Human
IFN b 1b Human
IFN b Mouse, His
IFI30 Human
IFN g Equine
IFN g Human
IFN g Human, His
IFN g Mouse
IFN g Rat
IFN tau Ovine
IFNA14 Human
IFNA7 Human
IFNG 139 a.a. Human
IFNG Canine
IFNG Human, HEK
IFNW1 Human
IRF 1 Human
IRF 2 Human
IRF 3 Human
IRF 5 Human

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