AssayPro—Rat beta 2-Microglobulin ELISA Kit(大鼠β2微球蛋白β2-MG酶联免疫试剂盒)
价格: ¥4480
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库存 :大量
供应商 :AssayPro
检测限 :0.2 ng/ml
检测方法 :ELISA
应用 :血清、血浆、细胞培养上清液
样本 :50 μl
规格 :96 wells
AssayMax Rat beta 2-Microglobulin ELISA Kit
大鼠β2微球蛋白β2-MG酶联免疫试剂盒
大鼠β2微球蛋白β2-MG酶联免疫试剂盒
Introduction
β2-Microglobulin (β2M) is a small serum protein that constitutes thelight chain of the major histocompatibility class I human leukocyteantigen (HLA class I), an integral membrane protein involved in theimmune response. The protein is 99 amino acid residues in length and hasmolecular mass of 12 kDa (1 - 4). β2M is released from the cell surfaceof HLA class I into the serum and carried to the kidneys for degradationand secretion (5). In chronic renal failure, β2M accumulates asinsoluble amyloid aggregates and causes arthralgias, destructiveosteoarthropathies, carpal tunnel syndrome and dialysis-relatedamyloidosis (6 - 8). Elevated serum β2M levels are associated with poorprognosis in multiple myeloma and lymphoma (9 - 12).
β2-Microglobulin (β2M) is a small serum protein that constitutes thelight chain of the major histocompatibility class I human leukocyteantigen (HLA class I), an integral membrane protein involved in theimmune response. The protein is 99 amino acid residues in length and hasmolecular mass of 12 kDa (1 - 4). β2M is released from the cell surfaceof HLA class I into the serum and carried to the kidneys for degradationand secretion (5). In chronic renal failure, β2M accumulates asinsoluble amyloid aggregates and causes arthralgias, destructiveosteoarthropathies, carpal tunnel syndrome and dialysis-relatedamyloidosis (6 - 8). Elevated serum β2M levels are associated with poorprognosis in multiple myeloma and lymphoma (9 - 12).
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