产品详情
文献和实验
相关推荐
库存 :大量
供应商 :AssayPro
检测限 :0.07 μg/ml
检测方法 :ELISA
应用 :血清、血浆
样本 :25 μl
规格 :96 wells
AssayMax Human Hemopexin ELISA Kit
血红素结合蛋白Hemopexin酶联免疫试剂盒
Introduction
血红素结合蛋白Hemopexin酶联免疫试剂盒
Hemopexin is a heme-binding plasma glycoprotein which, after haptoglobin, forms the second line of defense against hemoglobin-mediated oxidative damage during intravascular hemolysis. A decrease in plasma hemopexin concentration reflects a recent release of heme compounds in the extracellular compartment. Heme–hemopexin complexes are delivered to hepatocytes by receptor-mediated endocytosis after which hemopexin is recycled to the circulation (1). Studies indicated that increased hemopexin level associate with minimal change disease (2), sporadic Alzheimer's disease (3), heavy-drinking chronic alcoholics (4), hemolytic anemias, chronic neuromuscular diseases and acute intermittent porphyria (5).
Principal of the Assay
The AssayMax Human Hemopexin ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for detection of human hemopexin in plasma and serum. This assay employs a quantitative competitive enzyme immunoassay technique that measures human hemopexin in less than 2 hours. A polyclonal antibody specific for human hemopexin has been pre-coated onto a 96-well microplate with removable strips. Hemopexin in standards and samples is competed by a biotinylated hemopexin sandwiched by the immobilized antibody and streptavidin-peroxidase conjugate. All unbound material is then washed away and a peroxidase enzyme substrate is added. The color development is stopped and the intensity of the color is measured.
上海冠东生物科技有限公司
实名认证
金牌会员
入驻年限:12年