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英文名 ：Bovine Plasma Vitronectin
上海中乔新舟生物科技有限公司是美国Sciencell公司官网公布的一级代理商：美国ScienCell研究实验室（www.sciencellonline.com）成立于1999年，公司总部位于美国加州的圣地亚哥。主要致力于实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养基的研究和开发，在全球拥有众多客户。在国内销售15年来，很多老师应用其产品发表了高质量的SCI文章，且有着极高的文献引用率。凭借着严格的质控和优秀的产品品质，深受广大科研工作者的信赖。
ScienCell研究实验室生产的原代细胞、原代细胞专用培养基都经过了严格的质量控制，细胞纯度可达98％。其中包括21种人体正常细胞系统，90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离，产品质量过硬。确保了实验结果的重复性和连贯性。
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Description
Vitronectin is a glycoprotein found in plasma and extracellular matrix (ECM). It is a soluble, disulfide-linked dimer, composed of a75 kDa and a 65 kDa peptide chain. In blood and plasma, vitronectin is predominantly found as a single chain monomer. The N-terminal of vitronectin contains multiple binding sites for a variety of structures. Vitronectin is involved in a number of biological functions including cell adhesion, cell spreading and migration, cell proliferation, extracellular anchoring, fibrinolysis, hemostasis, and complement immune defense. Vitronectin can be used for coating tissue culture surfaces to promote cell adhesion, proliferation, and differentiation. Optimal conditions for cell attachment must be determined for each cell line and application.
ScienCell™ Bovine Plasma Vitronectin is purified from bovine plasma by affinity chromatography. It is supplied as a sterile solution in Dulbecco's Phosphate-Buffered Saline (DPBS).
Storage
It is recommended that the product be aliquoted and stored at -80°C. Vitronectin should be thawed slowly at 2-8°C with no agitation. Any precipitate that is present can be removed by centrifugation. Avoid repeated freeze/thaw cycles.
Reference
1. Vuento M, Korkolainen M, Kuusela P, Holtta E. (1985) “Isolation of a novel cell-attachment and spreading-promoting protein from human serum.” Biochem J. 227: 421-7.
2. Hayman EG, Pierschbacher MD, Suzuki S, Ruoslahti E. (1985) “Vitronectin--a major cell attachment promoting protein in fetal bovine serum.” Exp Cell Res. 160: 245-58.
3. Akiyama KS. (1999) “Purification of Vitronectin.” Current Protocols in Cell Biology. 10.6.1-10.6.5
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