人细胞纤连蛋白

价格： $198

品牌：ScienCell

货号：8488

产品详情

相关推荐

英文名：Human Cellular Fibronectin

上海中乔新舟生物科技有限公司是美国Sciencell公司官网公布的一级代理商：

美国ScienCell研究实验室（www.sciencellonline.com）成立于1999年，公司总部位于美国加州的圣地亚哥。主要致力于实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养基的研究和开发，在全球拥有众多客户。在国内销售15年来，很多老师应用其产品发表了高质量的SCI文章，且有着极高的文献引用率。凭借着严格的质控和优秀的产品品质，深受广大科研工作者的信赖。
ScienCell研究实验室生产的原代细胞、原代细胞专用培养基都经过了严格的质量控制，细胞纯度可达98％。其中包括21种人体正常细胞系统，90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离，产品质量过硬。确保了实验结果的重复性和连贯性。

请登录Sciencell公司官方网站（www.zqxzbio.com或www.sciencellonline.com）以确保购买正规公司产品。

Description

Fibronectin is a multi-domain glycoprotein composed of an array of multiple repeated modular structures. Cellular fibronectin, an adhesion glycoprotein of the extracellular matrix, exists as a dimer with a molecular mass of ~ 550 kDa. This structure is composed of two heterodimers, the A chain and the B chain containing the type III connecting segment region. Cellular fibronectin differs from plasma fibronectin by the presence of additional polypeptide segments and its capacity to specifically regulate morphology and growth of attached cells including stem cells. Multiple domains of fibronectin show binding affinities for collagen, fibrin, heparin, and specific cell membrane receptors including integrins, as well as modulate cell adhesion. Fibronectin matrix assembly is essential for normal development and contributes to the generation of tumor metastases.

ScienCell Human Cellular Fibronectin is produced from human fibroblasts maintained in serum-free media and then purified biochemically. This is supplied sterile in CAPS saline buffer.

Storage

It is recommended to store the product as single use aliquots at -80°C. Thawing should be done slowly at 2-8°C with no agitation. Material that fails to dissolve can be removed by centrifugation. Avoid repeating freeze/thaw cycles.

Reference

1. Yamada KM and Akiyama SK (1984). In Methods for preparation of media, supplements and substrata for serum-free animal cell culture. pp. 215-30. Alan R. Liss, Inc., New York.

2. Akiyama S et al. (1985). Fibronectin and fibronectin fragments in Extracellular Matrix: A Practical Approach, (New York), p. 183.

3. Potts JR and Campbell ID (1994). Fibronectin Structure and Assembly. Curr. Cell Bio, 6: 648-655.

4. Singh P, Schwarzbauer JE (2012). Fibronectin and stem cell differentiation - lessons from chondrogenesis. J Cell Sci, 15: 3703-12.