小鼠脊髓星形胶质细胞

小鼠脊髓星形胶质细胞

价格: $370

品牌:sciencell

货号:M1830-57

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CAS号 :00120303000

注册证号 :000132

物种来源 :小鼠

相关疾病 :

组织来源 :mouse

品系 :Mouse Neurons-dorsal spinal cord

ATCC Number :

细胞类型 :原代细胞

肿瘤类型 :

供应商 :中乔新舟

库存 :大量

免疫类型 :

细胞形态 :咨询销售

生长状态 :贴壁生长

年限 :5-10年

运输方式 :干冰

器官来源 :mouse

是否是肿瘤细胞 :不是

规格 :5 x 10^5 cells/vial

Sciencell公司产品由上海中乔新舟生物科技有限公司优质供应

美国ScienCell研究实验室(www.sciencellonline.com)成立于1999年,公司总部位于美国加州的圣地亚哥。主要致力
于实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养
基的研究和开发,在全球拥有众多客户。在国内销售15年来,很多老师应用其产品发表了高质量的SCI文章,且有着极高
的文献引用率。凭借着严格的质控和优秀的产品品质,深受广大科研工作者的信赖。

ScienCell研究实验室生产的原代细胞、原代细胞专用培养基都经过了严格的质量控制,细胞纯度可达98%。其中包括21
种人体正常细胞系统,90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离,产品质量过硬。
确保了实验结果的重复性和连贯性。

请登录Sciencell公司官方网站(www.zqxzbio.com www.sciencellonline.com )以确保购买正规公司产品

产品:小鼠脊髓星形胶质细胞
货号:M1830-57

Description

  Astrocytes are the major cell type in the mammalian brain. They have been implicated in a variety of
supportive functions for their partner neurons in the CNS, such as neuronal guidance during development,
ion and water homeostasis, blood flow regulation, neurotransmission, energy metabolism, and immune
defense [1]. Recent studies have shown that spinal cord astrocytes contribute to neuroinflammation by
chemokine expression which leads to the recruitment of “inflammatory” monocytes and neutrophils to
the lesion site [2]. Experimentally, spinal cord astrocytes have also been used to study the wobbler mutation
and muscular dystrophy in mice [3] and astrogliosis [4]. As the recognition of the importance of astrocytes
in nervous system functioning is increasing, specifically regarding the modulation of neural activity, astrocyte
cultures are continuing to provide a useful tool in exploring the diverse properties and functions of these cells.

  MA-sc from ScienCell Research Laboratories are isolated from neonatal C57BL/6 mouse spinal cord.
MA-sc are cryopreserved at primary culture and delivered frozen. Each vial contains >1 x 106 cells in 1 ml
volume. MA-sc are characterized by immunofluorescence with antibody specific to GFAP. MA-sc are negative
for mycoplasma, bacteria, yeast and fungi. MA-sc are guaranteed to further expand for 5 population doublings
in the condition provided by ScienCell Research Laboratories.

Recommended Medium
It is recommended to use Astrocyte Medium-animal (AM-a, Cat. #1831) for the culturing of MA-sc in vitro.

Product Use
MA-sc are for research use only. They are not approved for human or animal use, or for application in in
vitro diagnostic procedures.

Storage
Transfer cells directly and immediately from dry ice to liquid nitrogen upon receiving and keep the cells
in liquid nitrogen until cell culture is needed for experiments.

Shipping

Dry ice.
Reference

[1] Oberheim N, Goldman S, Nedergaard M. (2012) “Heterogeneity of astrocytic form and function.”
Methods in Mol Biol. 814: 23-45.
[2] Pineau I, Sun L, Bastien D, Lacroix S. (2010) “Astrocytes initiate inflammation in the injured mouse
spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor
/MyD88-depdent fashion.” Brain Behav Immun. 24: 540-53.
[3] Hantaz-Ambroise D, Blondet B, Murawsky M, Rieger F. (1994) “Abnormal astrocyte differentiation
and defective cellular interactions in wobbler mouse spinal cord.” J Neurocytol. 23: 179-92.
[4] Bhalala O, Pan L, Sahni V, McGuire T, Gruner K, Tourtellotte W, Kessler J. (2012) “microRNA-21
regulates astrocytic response following spinal cord injury.” J Neurosci. 32: 17935-47.

热烈祝贺上海中乔新舟生物科技有限公司成为美国Sciencell公司在中国正规一级代理商:

Sciencell公司产品由上海中乔新舟生物科技有限公司优质供应

近几年的新药研发成功率在逐年下降,其根本原因之一就是传统的药物筛选系统是建立在只具有30-40%
人类基因群的一系列细胞株上。这样一个有“缺陷型”药物筛选系统所产生的药物用于人体上就会出现许
多致命的弱点和不完整性。新一代药物筛选系统是含有一系列近乎完整的人类基因群的原代细胞株。而利
用这些原代细胞株所甄别和筛选出来的候选药物,其诊治人类疾病的成功几率将大大增加。这样不但大大
节省了新药的开发成本,而且将极大地提高人类的健康质量。这些产品从根本上提高了全球生命医学研究、
人类重要疾病药物研发、新药研发的成功率。
所以上海中乔新舟生物科技有限公司致力于提供优质原代细胞产品和完善的售后服务。

Sciencell公司部分原代细胞目录(如需要其他细胞资料请发邮件至 wwwfudan@163.com索取):

上海中乔新舟专长于为生物医药领域的医疗机构、研究中心、企业、临床医生等提供课题设计、基金联合申请、实验
技术服务、论文相关服务、采购外包等整体服务,目前已经成长为国内转化医学外包品牌。
中乔新舟的PI团队已经发展到专职PI 20人,联席PI 312人,其中大多数拥有海外背景。截止到2015年以PI或联席PI为
第一作者发表SCI 论文1682 篇(总IF 值为5721.82,其中影响因子IF>5.0 的论文216 篇,IF>10.0论文32 篇)。

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入驻年限:15年

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