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抗体名 ： PD-L1抗体
免疫原 ：Mouse IgG2b, κ
亚型 ：29E.2A3
级别 ：InVivoMab Antibodies
抗原来源 ：人，大小鼠
应用范围 ： in vitro PD-L1 blockade Functional assays Immunohistochemistry (frozen) Flow cytometry
是否单克隆 ：单克隆
抗体英文名 ：nVivoMAb anti-human PD-L1 (B7-H1)
适应物种 ：人
抗原 ：29E.2A3
规格 ：1mg
InVivoMAb anti-human PD-L1 (B7-H1)抗体PD-L1抗体
Bio X cel公司l通过大规模的组织培养生产抗体，亲和层析法纯化抗体，我们提供的抗体都是高纯度、低内毒素，无防腐剂和稳定剂，适用于临床前研究
| Isotype | Mouse IgG2b, κ |
| Recommended Isotype Control(s) | InVivoMAb mouse IgG2b isotype control, unknown specificity(BE0086) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Full length human PD-L1 |
| Reported Applications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
BioXcell BE0285-50MG InVivoMab anti-human PD-L1 (B7-H1) ￥24000
BioXcell BE0285-100MG InVivoMab anti-human PD-L1 (B7-H1) ￥35200
BioXcell BE0285-1MG InVivoMab anti-human PD-L1 (B7-H1) ￥1520
BioXcell BE0285-5MG InVivoMab anti-human PD-L1 (B7-H1) ￥5600
BioXcell BE0285-25MG InVivoMab anti-human PD-L1 (B7-H1) ￥14400
About InVivoMAb anti-human PD-L1 (B7-H1)
The 29E.2A3 monoclonal antibody reacts with human PD-L1 (programmed death ligand 1) also known as B7-H1 or CD274. PD-L1 is a 40 kDa type I transmembrane protein that belongs to the B7 family of the Ig superfamily. PD-L1 is expressed on T lymphocytes, B lymphocytes, NK cells, dendritic cells, as well as IFNγ stimulated monocytes, epithelial cells and endothelial cells. PD-L1 binds to its receptor, PD-1, found on CD4 and CD8 thymocytes as well as activated T and B lymphocytes and myeloid cells. Engagement of PD-L1 with PD-1 leads to inhibition of TCR-mediated T cell proliferation and cytokine production. PD-L1 is thought to play an important role in tumor immune evasion. Induced PD-L1 expression is common in many tumors and results in increased resistance of tumor cells to CD8 T cell mediated lysis. The 29E.2A3 antibody has been shown to block the binding of PD-1-Ig to PD-L1.
上海研卉生物科技有限公司
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入驻年限：10年
