文献支持重组人CD40L Receptor蛋白|重组人肿瘤坏死因子受体超家族成员 5蛋白

保存条件 ：Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.

英文名 ：Human CD40L Receptor Protein, mFc Tag

库存 ：999

供应商 ：卡梅德生物科技（天津）有限公司

规格 ：10ug/50ug

产品编号: KMP2287产品名称: Human CD40L Receptor Protein, mFc Tag中文名称: 重组人CD40L Receptor蛋白中文全称: 重组人肿瘤坏死因子受体超家族成员 5蛋白关键词: 肿瘤坏死因子受体超家族成员 5, Tumor Necrosis Factor Receptor Superfamily member 5, B-Cell Surface Antigen CD40, Bp50, CD40L Receptor, CDw40, CD40, TNFRSF5, Human CD40L Receptor Protein, mFc Tag, Recombinant Protein, KMP2287物种: Human宿主: HEK293 Cells规格: 50ug, 100ug, 200ug纯化方式: Affinity purification纯度: >95% as determined by SDS-PAGE内毒素水平: <1.0 EU/ug determined by the LAL method缓冲体系: PBS, pH7.4Uniprot: P25942SDS-PAGE: KMP2287 SDS-PAGE image1.png功能: Receptor for TNFSF5/CD40LG (PubMed:31331973).Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).产品背景: CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand(CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins(adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.说明: This product is for research use only.官网链接: https://www.kmdbioscience.cn/参考文献: J. Immunol. 203:1383-1391 (2019)