Anti-Phospho-JNK1-T183/Y185 + JNK2-T183/Y185+ JNK3-T221/Y223 Monoclonal Antibody

免疫原 ：A synthetic phosphorylated peptide around T183 & Y185 of human JNK1, JNK2 and JNK3

亚型 ：IgG

形态 ：液体

保存条件 ：Store at -20℃. Avoid freeze / thaw cycles.

克隆性 ：Monoclonal Antibody

目录编号 ：K010067M

库存 ：咨询客服

供应商 ：北京索莱宝科技有限公司

宿主 ：Rabbit

应用范围 ：WB

靶点 ：Phospho-JNK1-T183/Y185 + JNK2-T183/Y185+ JNK3-T221/Y223

抗体英文名 ：JNK1;JNK2;JNK3;PRKM8;SAPK1;SAPK1C

抗体名 ：0

规格 ：50ul

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]